Bioengineered brain targeting RVG‐modified BMSCs‐derived small extracellular vesicles loaded with miR‐21 alleviate excessive autophagic neuronal injury after cerebral ischaemia via PTEN/Akt/mTOR pathway. ABSTRACT Ischaemic stroke (IS) leads to tragic disability and high adult mortality, while there are limited therapeutic measures for it.
Yiyang Li +9 more
wiley +1 more source
Carotid endarterectomy with active extracorporeal perfusion for bilateral ocular ischemic syndrome in a patient with a preoperatively defined critical single-vessel cerebral supply on four-dimensional flow magnetic resonance imaging. [PDF]
Millinger J +5 more
europepmc +1 more source
A transient ensemble of convection‐permitting climate simulations is used to compute bias‐corrected user‐relevant climate indices for Germany under recent and future climate conditions, both considering high spatial resolution and uncertainty estimations. For high temperature indices, a clear increase is observed, for example, for hot days and tropical
Joaquim G. Pinto +6 more
wiley +1 more source
Lightweight Safety Helmet Wearing Detection Algorithm Based on GSA-YOLO. [PDF]
Wang H, Zhou Q, Hao Z, Xiao W, Yan L.
europepmc +1 more source
Spatiotemporal Changes in Precipitation Concentration in the Atlantic‐European Region
This study analyses changes in precipitation concentration using ERA5 and E‐OBS datasets. Gini index as a measure of precipitation concentration revealed a gradual expansion of areas with increasing unevenness in precipitation distribution across the Atlantic‐European region since 1961.
Petr Dobrovolný +4 more
wiley +1 more source
Dynamic changes in phycosphere carbonate chemistry reveal rapid modulation of carbon uptake in single diatom cells. [PDF]
Keys M +5 more
europepmc +1 more source
openaire +1 more source
Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang +8 more
wiley +1 more source
Functional Characterization of a Root-Preferential and Stress-Inducible Promoter of Eca-miR482f in <i>Eucalyptus camaldulensis</i>. [PDF]
Zhang W, Zhou Q, Wu X, Huang S, Lin Y.
europepmc +1 more source

