Results 101 to 110 of about 1,406 (212)

Extrachromosomal circular DNA-related SPOCK1 contributes to development and enzalutamide resistance of prostate cancer by regulating epithelial mesenchymal transition

open access: yesHeliyon
Prostate cancer is a significant contributor to cancer-related mortality, and the tumor typically develops into castration-resistant prostate cancer (CRPC).
Yicong Yao   +9 more
doaj   +1 more source

Categorizing Extrachromosomal Circular DNA as Biomarkers in Serum of Cancer

open access: yesBiomolecules
Extrachromosomal circular DNA (eccDNA), a double-stranded circular DNA molecule found in multiple organisms, has garnered an increasing amount of attention in recent years due to its close association with the initiation, malignant progression, and ...
Enze Deng, Xiaoying Fan
doaj   +1 more source

The eccDNA mediated spread and rapid evolution of herbicide resistance in pigweed interspecific hybrids [PDF]

open access: gold, 2023
Dal‐Hoe Koo   +7 more
openalex   +1 more source

Molecular mechanisms of adaptive evolution revealed by global selection for glyphosate resistance [PDF]

open access: yes, 2019
The human‐directed, global selection for glyphosate resistance in weeds has revealed a fascinating diversity of evolved resistance mechanisms, including herbicide sequestration in the vacuole, a rapid cell death response, nucleotide polymorphisms in the ...
Gaines, T. A.   +2 more
core   +1 more source

Amplification of a Zygosaccharomyces bailii DNA Segment in Wine Yeast Genomes by Extrachromosomal Circular DNA Formation [PDF]

open access: yes, 2011
We recently described the presence of large chromosomal segments resulting from independent horizontal gene transfer (HGT) events in the genome of Saccharomyces cerevisiae strains, mostly of wine origin.
A Toh-e   +68 more
core   +2 more sources

Atlas of eccDNA in Mus musculus reveals intron and isoform gene-density dependent protection of transcription-induced eccDNA formation

open access: yes
Abstract EccDNA is a driver of many cancers and a potential intermediate in other age-related disorders. However, little is known about the mechanisms underlying eccDNA formation in healthy tissue and how age affects these processes. We generated an Atlas of eccDNA across seven tissues of mice spanning four ages. EccDNA was overrepresented from
Birgitte Regenberg   +11 more
openaire   +1 more source

The important role of the eccDNA in tumors

open access: yesAnnals of Translational Medicine, 2022
Sun, Zhenguo, Tian, Hui
openaire   +2 more sources

Identification and Characterization of Extrachromosomal Circular DNA in Plasma of Lung Adenocarcinoma Patients

open access: yesInternational Journal of General Medicine, 2022
Xiaoqiong Wu,1,* Pu Li,1,* Maimaitiaili Yimiti,1 Zhiqiu Ye,2 Xuqian Fang,2 Peizhan Chen,3 Zhidong Gu1,4 1Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China ...
Wu X   +6 more
doaj  

Data from Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation

open access: gold, 2023
Pankaj Kumar   +5 more
openalex   +1 more source

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