Diverse and mobile:
, 2022 Kornelia Kwolek +6 more
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Comparative analysis of methodologies for detecting extrachromosomal circular DNA
Nature CommunicationsExtrachromosomal circular DNA (eccDNA) is crucial in oncogene amplification, gene transcription regulation, and intratumor heterogeneity. While various analysis pipelines and experimental methods have been developed for eccDNA identification, their ...
Xuyuan Gao +10 more
doaj +1 more source
Extrachromosomal circular DNA and their roles in cancer progression
Genes and DiseasesExtrachromosomal circular DNA (eccDNA), a chromosome-independent circular DNA, has garnered significant attention due to its widespread distribution and intricate biogenesis in carcinoma.
Siqi Zheng +6 more
doaj +1 more source
Development of \u3cem\u3eCutaneotrichosporon oleaginosus\u3c/em\u3e to Convert Lignin-Derived Phenolics to Oleochemicals [PDF]
, 2020 Oleaginous yeasts have long been a target for developing industrial-scale biorefineries due to their ability to accumulate high amounts of lipids, synthesize complex chemicals and proteins, and robustly metabolize diverse feedstocks.
Yaguchi, Allison
core +1 more source
Retrotransposons hijack alt-EJ DNA repair process for mobilization and eccDNA biogenesis [PDF]
, 2022 Fu Yang +6 more
openalex +1 more source
Figure S1 & Figure S2 from Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation [PDF]
, 2023 Pankaj Kumar +5 more
openalex +1 more source
Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon [PDF]
Long terminal repeat retrotransposons (LTR-RTs) are powerful mutagens regarded as a major source of genetic novelty and important drivers of evolution.
Blevins, Todd +14 more
core +1 more source
Genome-wide sequencing identified extrachromosomal circular DNA as a transcription factor-binding motif of the senescence genes that govern replicative senescence in human mesenchymal stem cells [PDF]
IntroductionMesenchymal stem cells (MSCs) have long been postulated as an important source cell in regenerative medicine. During subculture expansion, mesenchymal stem cell (MSC) senescence diminishes their multi-differentiation capabilities, leading to ...
Boyu Liao +12 more
core +1 more source
Models of evolutionary rescue of bacteria and yeast by extrachromosomal genetic elements [PDF]
Many organisms contain extrachromosomal genetic elements, additional components of the genome outside of the main chromosomal component. Mathematical modelling has already made an extensive contribution to the theoretical population genetics of normal ...
Dewan, Ian Alexander
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