Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon [PDF]
Long terminal repeat retrotransposons (LTR-RTs) are powerful mutagens regarded as a major source of genetic novelty and important drivers of evolution.
Blevins, Todd +14 more
core +1 more source
eccDNA purification, full-length sequencing, and genomic mapping [PDF]
, 2022 Yuangao Wang, Meng Wang, Yi Zhang
openalex +1 more source
Models of evolutionary rescue of bacteria and yeast by extrachromosomal genetic elements [PDF]
Many organisms contain extrachromosomal genetic elements, additional components of the genome outside of the main chromosomal component. Mathematical modelling has already made an extensive contribution to the theoretical population genetics of normal ...
Dewan, Ian Alexander
core
Genome-wide sequencing identified extrachromosomal circular DNA as a transcription factor-binding motif of the senescence genes that govern replicative senescence in human mesenchymal stem cells [PDF]
IntroductionMesenchymal stem cells (MSCs) have long been postulated as an important source cell in regenerative medicine. During subculture expansion, mesenchymal stem cell (MSC) senescence diminishes their multi-differentiation capabilities, leading to ...
Boyu Liao +12 more
core +1 more source
Characterizing Gene Amplifications in Extrachromosomal Circular DNA (eccDNA) of Colon Cancer
Extrachromosomal circular DNA (eccDNA) exists outside the linear chromosomes and, while present in normal cells, takes on a more critical role in cancer [1]. It can harbor oncogenes and regulatory elements that drive tumorigenesis. In the case of colon cancer, which is the third most common cancer worldwide [2], eccDNA may be especially impactful.
Mufeed, Talha +2 more
openaire +2 more sources
Development of \u3cem\u3eCutaneotrichosporon oleaginosus\u3c/em\u3e to Convert Lignin-Derived Phenolics to Oleochemicals [PDF]
, 2020 Oleaginous yeasts have long been a target for developing industrial-scale biorefineries due to their ability to accumulate high amounts of lipids, synthesize complex chemicals and proteins, and robustly metabolize diverse feedstocks.
Yaguchi, Allison
core +1 more source
HeliyonProstate cancer is a significant contributor to cancer-related mortality, and the tumor typically develops into castration-resistant prostate cancer (CRPC).
Yicong Yao +9 more
doaj
Table S2 from Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation [PDF]
, 2023 Pankaj Kumar +5 more
openalex +1 more source
That's no moon, it's a Starship:Giant transposons driving fungal horizontal gene transfer [PDF]
, 2023 Bucknell, Angus, McDonald, Megan
core +1 more source