Results 121 to 130 of about 1,406 (212)

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Extrachromosomal circular miRNA-gene amplifications contribute to the renal cancer phenotype

Cell Reports
Summary: Megabase-sized extrachromosomal circular DNA with intact oncogenes (ecDNA) plays crucial roles in cancer. However, the impact of smaller (100 bp–1 Mb), more ubiquitous extrachromosomal circular DNA (eccDNA) on tumor pathology is unclear.
Peng Han, Wei Lv, Zhe Xu, Tianxi Yu, Shan Gao, Xi Xiang, Xiaoguang Pan, Yuchen Zeng, Jakob Hull Havgaard, Jan Gorodkin, Xue Liang, Shuang Wu, Huiying Tao, Xiaolong Sui, Wenting Wang, Wei Dong, Huanming Yang, Chunhua Lin, Birgitte Regenberg   +18 more
doaj   +1 more source

Extrachromosomal Circular DNA: Current Knowledge and Implications for CNS Aging and Neurodegeneration [PDF]

, 2020
Ain, Quratul, Kretz, Alexandra, Schmeer, Christian, Wengerodt, Diane, Witte, Otto W.   +4 more
core   +1 more source

A comprehensive study of extrachromosomal circular DNA in pancreatic ductal adenocarcinoma [PDF]

Introduction: Extrachromosomal circular DNAs (eccDNA) vary in sizes and drive many aspects of tumour biology, including drug resistance and oncogene amplification.
Schreyer, Daniel
core   +1 more source

Increased serum extrachromosomal circular DNA SORBS1circle level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus

Cellular & Molecular Biology Letters
Background Extrachromosomal circular DNAs (eccDNAs) exist in human blood and somatic cells, and are essential for oncogene plasticity and drug resistance. However, the presence and impact of eccDNAs in type 2 diabetes mellitus (T2DM) remains inadequately
Xiang Kong, Shu-jun Wan, Tian-bing Chen, Lan Jiang, Yu-jie Xing, Ya-ping Bai, Qiang Hua, Xin-ming Yao, Yong-li Zhao, Hong-mei Zhang, De-guo Wang, Qing Su, Kun Lv   +12 more
doaj   +1 more source

Dynamics of extrachromosomal circular DNA in rice

Nature Communications
The genome’s dynamic nature, exemplified by elements like extrachromosomal circular DNA (eccDNA), is crucial for biodiversity and adaptation. Yet, the role of eccDNA in plants, particularly rice, remains underexplored.
Jundong Zhuang, Yaoxin Zhang, Congcong Zhou, Danlin Fan, Tao Huang, Qi Feng, Yiqi Lu, Yan Zhao, Qiang Zhao, Bin Han, Tingting Lu   +10 more
doaj   +1 more source

Magnaporthe oryzae eccDNA manuscript analysis files

, 2022
Pierre M. Joubert
openalex   +1 more source

CRISPR-C:circularization of genes and chromosome by CRISPR in human cells [PDF]

, 2018
Bolund, Lars, Church, George M., Huang, Jinrong, Jensen, Uffe Birk, Kjeldsen, Eigil, Lin, Lin, Liu, Xin, Luo, Yonglun, Møller, Henrik Devitt, Petersen, Trine Skov, Regenberg, Birgitte, Wang, Jian, Xiang, Xi, Xu, Xun, Yang, Huanming, Yang, Luhan, Zhang, Xiuqing   +16 more
core   +1 more source

Impact of novel eccDNA-driven drivers on tumorigenesis and prognosis.

Yuxi Gu (11386081), Yidan Song (4451473), Jun Liu (42548)   +2 more
openalex   +1 more source

Identification and Characterization of eccDNA in HepG2 Cells Under DOX-Induced DNA Damage. [PDF]

Int J Mol Sci
Zhang J, Li Y, Chen W, Du X, Zheng J, Chen J, Huang X, Pang C, Guo Z.   +8 more
europepmc   +1 more source