Results 131 to 140 of about 1,090 (186)

Increased serum extrachromosomal circular DNA SORBS1circle level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus

Cellular & Molecular Biology Letters
Background Extrachromosomal circular DNAs (eccDNAs) exist in human blood and somatic cells, and are essential for oncogene plasticity and drug resistance. However, the presence and impact of eccDNAs in type 2 diabetes mellitus (T2DM) remains inadequately
Xiang Kong, Shu-jun Wan, Tian-bing Chen, Lan Jiang, Yu-jie Xing, Ya-ping Bai, Qiang Hua, Xin-ming Yao, Yong-li Zhao, Hong-mei Zhang, De-guo Wang, Qing Su, Kun Lv   +12 more
doaj   +1 more source

Circle-seq based method for eccDNA synthesis and its application as a canonical promoter independent vector for robust microRNA overexpression

Computational and Structural Biotechnology Journal, 2023
Jiaying Yu, Haoran Zhang, Peng Han, Xianming Jiang, Jing Li, Bo Li, Shaohua Yang, Chunxiao He, Shuang Mao, Yonghui Dang, Xi Xiang   +10 more
semanticscholar   +1 more source

Two important players in poor prognosis hepatocellular carcinoma (HCC): Extrachromosomal circular DNA (eccDNA) and its passenger, the oncogenic miR-17~92 locus.

Hepatology, 2023
O. Andrisani
semanticscholar   +1 more source

Dynamics of extrachromosomal circular DNA in rice

Nature Communications
The genome’s dynamic nature, exemplified by elements like extrachromosomal circular DNA (eccDNA), is crucial for biodiversity and adaptation. Yet, the role of eccDNA in plants, particularly rice, remains underexplored.
Jundong Zhuang, Yaoxin Zhang, Congcong Zhou, Danlin Fan, Tao Huang, Qi Feng, Yiqi Lu, Yan Zhao, Qiang Zhao, Bin Han, Tingting Lu   +10 more
doaj   +1 more source

UEG Week 2024 Moderated Posters

United European Gastroenterology Journal, Volume 12, Issue S8, Page 201-664, October 2024.
wiley   +1 more source

A comprehensive study of extrachromosomal circular DNA in pancreatic ductal adenocarcinoma [PDF]

Introduction: Extrachromosomal circular DNAs (eccDNA) vary in sizes and drive many aspects of tumour biology, including drug resistance and oncogene amplification.
Schreyer, Daniel
core   +1 more source

Sequence characterization of eccDNA content in glyphosate sensitive and resistant Palmer amaranth from geographically distant populations

, 2022
Hailey Spier Camposano, William T. Molin, Christopher Saski   +2 more
openalex   +2 more sources

Sequence characterization of eccDNA content in glyphosate sensitive and resistant Palmer amaranth from geographically distant populations [PDF]

, 2021
Hailey Spier Camposano, William T. Molin, Christopher Saski   +2 more
openalex   +1 more source

Predicting gestational diabetes mellitus risk at 11–13 weeks’ gestation: the role of extrachromosomal circular DNA

Cardiovascular Diabetology
Background Gestational diabetes mellitus (GDM) significantly impacts maternal and infant health both immediately and over the long term, yet effective early diagnostic biomarkers are currently lacking.
Jin Wang, Pengyu Huang, Fei Hou, Dongdong Hao, Wushan Li, Hua Jin   +5 more
doaj   +1 more source

CRISPR-C:circularization of genes and chromosome by CRISPR in human cells [PDF]

, 2018
Bolund, Lars, Church, George M., Huang, Jinrong, Jensen, Uffe Birk, Kjeldsen, Eigil, Lin, Lin, Liu, Xin, Luo, Yonglun, Møller, Henrik Devitt, Petersen, Trine Skov, Regenberg, Birgitte, Wang, Jian, Xiang, Xi, Xu, Xun, Yang, Huanming, Yang, Luhan, Zhang, Xiuqing   +16 more
core   +1 more source