Molecular characterization of cell-free eccDNAs in human plasma [PDF]
Scientific Reports, 2017 AbstractExtrachromosomal circular DNAs (eccDNAs) have been reported in most eukaryotes. However, little is known about the cell-free eccDNA profiles in circulating system such as blood. To characterize plasma cell-free eccDNAs, we performed sequencing analysis in 26 libraries from three blood donors and negative controls.
Songbin Fu +6 more
openaire +4 more sources
Circulomics: Ultrasensitive Characterization of Extrachromosomal Circular DNA (eccDNA) Distributions and Functions in Eukaryotes [PDF]
Biophysical Journal, 2018 Massa J. Shoura +2 more
openalex +3 more sources
Extracellular DNA secreted in yeast cultures is metabolism-specific and inhibits cell proliferation [PDF]
, 2023 Extracellular DNA (exDNA) can be actively released by living cells and different putative functions have been attributed to it. Further, homolo-gous exDNA has been reported to exert species-specific inhibitory effects on several organisms.
Bonanomi G. +19 more
core +1 more source
Investigating the origins and evolution of a glyphosate-resistant weed invasion in South America [PDF]
, 2021 The global invasion, and subsequent spread and evolution of weeds provides unique opportunities to address fundamental questions in evolutionary and invasion ecology. Amaranthus palmeri is a widespread glyphosate-resistant (GR) weed in the USA.
Gaines, Todd A +9 more
core +2 more sources
Epigenetics, 2023 To explore the presence of extrachromosomal circular DNA (eccDNA) in the anterior capsule of the lens in the eyes of patients with cataract and with high myopia.
Kai Wen +11 more
doaj +1 more source
Extrachromosomal circular DNA: biogenesis, structure, functions and diseases
Signal Transduction and Targeted Therapy, 2022 Extrachromosomal circular DNA (eccDNA), ranging in size from tens to millions of base pairs, is independent of conventional chromosomes. Recently, eccDNAs have been considered an unanticipated major source of somatic rearrangements, contributing to ...
Ludi Yang +6 more
doaj +1 more source
Extrachromosomal DNA in Genome (in)Stability – Role of Telomeres [PDF]
, 2016 Eukaryotic genome consists of long linear chromosomes. It is complex in its content and has dynamic features. It mostly consists of non-coding DNA of various repeats, often prone to recombination including creation of extrachromosomal DNA which can be re-
Nanić, Lucia +2 more
core +3 more sources
Cells, 2023 Cell-free (cf) extrachromosomal circular DNA (eccDNA) has a potential clinical application as a biomarker. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a complex immunological pathogenesis, associated with autoantibody ...
Daniela Gerovska +1 more
doaj +1 more source
Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells [PDF]
, 2016 Extrachromosomal circular DNAs (eccDNAs) are common genetic elements in Saccharomyces cerevisiae and are reported in other eukaryotes as well. EccDNAs contribute to genetic variation among somatic cells in multicellular organisms and to evolution of ...
Bojsen, Rasmus Kenneth +5 more
core +2 more sources
Drosophila melanogaster linker histone dH1 is required for transposon silencing and to preserve genome integrity [PDF]
, 2012 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial LicenseHistone H1 is an intrinsic component of chromatin, whose important contribution to chromatin structure is well-established in vitro ...
Azorín, Ferran +5 more
core +3 more sources