Results 51 to 60 of about 1,406 (212)
Sequence Characterization of Extra-Chromosomal Circular DNA Content in Multiple Blackgrass (Alopecurus myosuroides) Populations. [PDF]
, 2023 Alopecurus myosuroides (blackgrass) is a problematic weed of Western European winter wheat, and its success is largely due to widespread multiple-herbicide resistance. Previous analysis of F2 seed families derived from two distinct blackgrass populations
Comont, D. +3 more
core +1 more source
Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells [PDF]
, 2016 Extrachromosomal circular DNAs (eccDNAs) are common genetic elements in Saccharomyces cerevisiae and are reported in other eukaryotes as well. EccDNAs contribute to genetic variation among somatic cells in multicellular organisms and to evolution of ...
Bojsen, Rasmus Kenneth +5 more
core +2 more sources
Extrachromosomal circular DNA: biogenesis, structure, functions and diseases
Signal Transduction and Targeted Therapy, 2022 Extrachromosomal circular DNA (eccDNA), ranging in size from tens to millions of base pairs, is independent of conventional chromosomes. Recently, eccDNAs have been considered an unanticipated major source of somatic rearrangements, contributing to ...
Ludi Yang +6 more
doaj +1 more source
Evidence for rolling circle replication of tandem genes in Drosophila [PDF]
, 2005 Extrachromosomal circular DNA (eccDNA) is one characteristic of the plasticity of the eukaryotic genome. It is found in various organisms and contains sequences derived primarily from repetitive chromosomal DNA.
Agmon, Neta +4 more
core +3 more sources
Molecular characterization of cell-free eccDNAs in human plasma [PDF]
Scientific Reports, 2017 AbstractExtrachromosomal circular DNAs (eccDNAs) have been reported in most eukaryotes. However, little is known about the cell-free eccDNA profiles in circulating system such as blood. To characterize plasma cell-free eccDNAs, we performed sequencing analysis in 26 libraries from three blood donors and negative controls.
Jing Zhu +5 more
openaire +3 more sources
Extrachromosomal circular DNA: Current status and future prospects
eLife, 2022 Extrachromosomal circular DNA (eccDNA) is a double-stranded DNA molecule found in various organisms, including humans. In the past few decades, the research on eccDNA has mainly focused on cancers and their associated diseases.
Yiheng Zhao +4 more
doaj +1 more source
Cells, 2023 Cell-free (cf) extrachromosomal circular DNA (eccDNA) has a potential clinical application as a biomarker. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a complex immunological pathogenesis, associated with autoantibody ...
Daniela Gerovska +1 more
doaj +1 more source
Deciphering extrachromosomal circular DNA in Arabidopsis
Computational and Structural Biotechnology Journal, 2021 Extrachromosomal circular DNA (eccDNA) is independent of the chromosome and exists in many eukaryotes. However, the nature and origin of eccDNA in plants remains unclear.
Keyi Wang +15 more
doaj +1 more source
Transcription-induced formation of extrachromosomal DNA during yeast ageing.
PLoS Biology, 2019 Extrachromosomal circular DNA (eccDNA) facilitates adaptive evolution by allowing rapid and extensive gene copy number variation and is implicated in the pathology of cancer and ageing.
Ryan M Hull +5 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2022 Extrachromosomal circular DNA (eccDNA) of chromosomal origin is common in eukaryotic cells. Amplification of oncogenes on large eccDNA (ecDNA) can drive biological processes such as tumorigenesis, and identification of eccDNA by sequencing after removal ...
Weijia Feng +8 more
doaj +1 more source