Results 81 to 90 of about 18,098 (209)
A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy +10 more
wiley +1 more source
ABSTRACT This case highlights that an early pathological fracture may occur after curettage and synthetic bone grafting for a distal femoral liposclerosing myxofibrous tumor despite prophylactic fixation. Prompt revision with graft debridement, autologous iliac crest grafting, and stable distal femoral plate fixation can achieve fracture union, pain ...
Yingsong Yuan, Yang Gu
wiley +1 more source
Macroglossia and periorbital ecchymosis [PDF]
Nely Mercy, Díaz Mejía +2 more
openaire +2 more sources
Infant With Unilateral Periorbital Ecchymosis [PDF]
Joshua K, Dodderer +2 more
openaire +2 more sources
Premature interruption of dual antiplatelet therapy in a patient with polycythemia vera and clinically suspected acquired von Willebrand syndrome triggered catastrophic recurrent stent thrombosis, whereas perioperative bridging with eptifibatide enabled safe surgery. ABSTRACT Polycythemia vera is associated with a thrombotic–hemorrhagic paradox.
Behrouz zarei +2 more
wiley +1 more source
ABSTRACT Background and Aims Neuroblastoma is the most common extracranial solid tumor and contributes the most to pediatric oncology deaths worldwide. Its clinical manifestations are heterogeneous, including relapses, and the prognosis remains poor, especially for high‐risk patients.
Mosammat Jannatul Mawa +3 more
wiley +1 more source
Abstract Purpose The present study aimed to compare the efficacy and safety of a combined injection of stromal vascular fraction (SVF) and platelet rich plasma (PRP) versus a high molecular weight (HMW) hyaluronic acid (HA) injection in patients with knee osteoarthritis (KOA).
Trifon Totlis +6 more
wiley +1 more source
Background: Surgical site infection (SSI) is a frequent complication following cesarean section and contributes substantially to maternal morbidity. With increasing cesarean delivery rates and limited resources in public hospitals, there is a pressing ...
Swarnima Agrawal +3 more
doaj +1 more source
Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden +3 more
wiley +1 more source
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg +7 more
wiley +1 more source

