Results 61 to 70 of about 972 (174)

A Rare Case of Pigmented Eccrine Poroma on the Trunk Mimicking Malignant Melanoma

Clinical Case Reports, Volume 12, Issue 12, December 2024.
ABSTRACT Representative clinical images in this study can increase awareness regarding the clinical similarity between this benign adnexal tumor and malignant melanoma and highlight the importance of pathological examination.
Saman Al‐Zahawi, Alireza Ghanadan, HamidReza Mahmoudi, Zahra Razavi   +3 more
wiley   +1 more source

Porocarcinomas with PAK1/2/3 fusions: a series of 12 cases

Histopathology, Volume 85, Issue 4, Page 566-578, October 2024.
Recurrent PAK1/2/3 fusions are detected in a subset of porocarcinomas with frequent follicular and sebaceous differentiation. Aims Porocarcinoma is a malignant sweat gland tumour differentiated toward the upper part of the sweat duct and may arise from the transformation of a preexisting benign poroma. In 2019, Sekine et al.
Thibault Kervarrec, Danna Westphal, Daniel Pissaloux, Mélanie Legrand, Franck Tirode, Anne Neuhart, Francoise Drouot, Jürgen C Becker, Nicolas Macagno, Alice Seris, Thomas Jouary, Fanny Beltzung, Marie‐Laure Jullie, Paul W Harms, Bernard Cribier, Samia Mourah, Fanélie Jouenne, Gaelle Fromont, Baptiste Louveau, Maxence Mancini, Dmitry V Kazakov, Arnaud de la Fouchardière, Maxime Battistella   +22 more
wiley   +1 more source

Gene expression profiling in porocarcinoma indicates heterogeneous tumor development and substantiates poromas as precursor lesions

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 8, Page 1115-1124, August 2024.
Summary Background and objectives Malignant sweat gland tumors are rare, with the most common being eccrine porocarcinoma (EP). Approximately 18% of benign eccrine poroma (EPO) transit to EP. Previous research has provided first insights into the mutational landscape of EP. However, only few studies have performed gene expression analyses.
Svenja Holst, Anna K. Weber, Friedegund Meier, Jörg Otte, Patrick Petzsch, Julia Reifenberger, Thorsten Wachtmeister, Dana Westphal, Mirjana Ziemer, Wasco Wruck, James Adjaye, Regina C. Betz, Arno Rütten, Harald M. Surowy, Silke Redler   +14 more
wiley   +1 more source

Genexpressionsprofile beim Porokarzinom deuten auf heterogene Tumorentwicklung hin und untermauern Porome als Vorläuferläsionen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 8, Page 1115-1125, August 2024.
Zusammenfassung Hintergrund und Ziele Maligne Schweißdrüsentumoren sind selten, wobei das ekkrine Porokarzinom (EP) das häufigste ist. Etwa 18 % der benignen ekkrinen Porome (EPO) entwickeln sich zum EP. Wissenschaftliche Studien haben erste Einblicke in die Mutationslandschaft von EPs geliefert.
Svenja Holst, Anna K. Weber, Friedegund Meier, Jörg Otte, Patrick Petzsch, Julia Reifenberger, Thorsten Wachtmeister, Dana Westphal, Mirjana Ziemer, Wasco Wruck, James Adjaye, Regina C. Betz, Arno Rütten, Harald M. Surowy, Silke Redler   +14 more
wiley   +1 more source

Porocarcinoma: relato de caso Porocarcinoma: case report

Anais Brasileiros de Dermatologia, 2011
O porocarcinoma écrino é uma neoplasia maligna, rara, das glândulas sudoríparas écrinas e, com maior frequência, acomete os indivíduos idosos, com idade média de 67,5 anos.
Fabiana Dutra Uchôa Cursino, Lucíola Teixeira, Emerson de Andrade Lima, Mariana de Andrade Lima, Silvia Costa Carvalho Rodrigues, Daniela Takano   +5 more
doaj   +1 more source

Eccrine Poroma: Pathogenesis, New Diagnostic Tools and Association with Porocarcinoma—A Review

Diagnostics, 2023
Eccrine poroma (EP) is a relatively rare benign adnexal neoplasm that usually affects elderly patients. Its pathogenesis is still under investigation, but recent gene studies have revealed gene fusions as key incidences resulting in oncogenetic pathways.
Eirini Kyrmanidou, Christina Fotiadou, Christina Kemanetzi, Myrto-Georgia Trakatelli, Anastasia Trigoni, Aikaterini Patsatsi, Zoe Apalla, Elizabeth Lazaridou   +7 more
doaj   +1 more source

Primary cutaneous NUT carcinoma with BRD4::NUTM1 fusion

Journal of Cutaneous Pathology, Volume 51, Issue 6, Page 424-429, June 2024.
Abstract Nuclear protein in testis (NUT) carcinoma, molecularly defined by the NUTM1 gene rearrangement, is most commonly reported in young adults in the sinonasal tract, nasopharynx, or thorax. At these sites, NUT carcinoma is an extremely aggressive malignancy with dismal prognosis. Recently, five cases of primary cutaneous NUT adnexal carcinoma have
Ahmed Shah, Adrian Box, Thomas Brenn, Ashley Flaman   +3 more
wiley   +1 more source

TGFβ‐induced EN1 promotes tumor budding of adenoid cystic carcinoma in patient‐derived organoid model

International Journal of Cancer, Volume 154, Issue 10, Page 1814-1827, 15 May 2024.
What's new? Accurate diagnosis of adenoid cystic carcinoma (ACC) often requires distinction from basal cell adenoma (BCA). Diagnostic markers capable of differentiating ACC from BCA, however, are lacking. Here, the authors investigated the diagnostic potential of homeobox transcription factor EN1.
Zhixuan Hui, Bo Wang, Zhengyan Liu, Jinhui Wei, Jiaxing Gan, Marene Landstrom, Yabing Mu, Guangxiang Zang   +7 more
wiley   +1 more source

Eccrine Porocarcinoma Associated with an Eccrine Poroma

Online Journal of Health & Allied Sciences, 2014
Eccrine porocarcinoma is a rare carcinoma arising from the intraepidermal duct of eccrine sweat glands and constitute about 0.005% of epithelial cutaneous neoplasms.
Manimaran D, Thulasi RR, Hemanathan G, Ishwarya S, Anuradha S   +4 more
doaj  

Treatment of eccrine porocarcinoma with metastasis to the parotid gland using intensity-modulated radiation therapy: a case report

Journal of Medical Case Reports, 2010
Introduction Cutaneous eccrine porocarcinomas are uncommon malignant tumors of the sweat gland. Case Presentation A 76-year-old Caucasian man presented to our hospital with a left temporal mass. We describe a case of eccrine porocarcinoma with metastasis
Lentsch Eric J, Bilic Masha, Zauls A, Zeidan Youssef H, Sharma Anand K   +4 more
doaj   +1 more source