The role of (line‐field confocal) optical coherence tomography and reflectance confocal microscopy in the diagnosis of a malignant eccrine differentiated sweat gland tumour with features of a porocarcinoma and an eccrine spiradenocarcinoma: a case report [PDF]
Malignant eccrine differentiated sweat gland tumours, including porocarcinoma and eccrine spiradenocarcinoma, are rare and aggressive neoplasms that pose diagnostic and therapeutic challenges.
Bachter, Uta+10 more
core +3 more sources
Eccrine Sweat Gland and Its Regeneration: Current Status and Future Directions. [PDF]
Eccrine sweat glands (ESGs) play an important role in temperature regulation by secreting sweat. Insufficiency or dysfunction of ESGs in a hot environment or during exercise can lead to hyperthermia, heat exhaustion, heatstroke, and even death, but the ...
Lin Y+6 more
europepmc +2 more sources
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. [PDF]
Eccrine sweat glands are essential for sweating and thermoregulation in humans. Loss-of-function mutations in the Ca2+ release-activated Ca2+ (CRAC) channel genes ORAI1 and STIM1 abolish store-operated Ca2+ entry (SOCE), and patients with these CRAC ...
Concepcion AR+17 more
europepmc +2 more sources
The microfluidics of the eccrine sweat gland, including biomarker partitioning, transport, and biosensing implications. [PDF]
Non-invasive and accurate access of biomarkers remains a holy grail of the biomedical community. Human eccrine sweat is a surprisingly biomarker-rich fluid which is gaining increasing attention.
Sonner Z+10 more
europepmc +2 more sources
Metastatic sweat gland adenocarcinoma: A clinico-pathological dilemma [PDF]
Background Sweat gland adenocarcinoma is a rare malignancy with high metastatic potential seen more commonly in later years of life. Scalp is the most common site of occurrence and it usually spreads to lymph nodes.
Saxena Sunita+5 more
doaj +3 more sources
Neoplasms of sweat glands and the breast may be morphologically and immunophenotypically similar. A recent study showed that TRPS1 staining is a highly sensitive and specific marker for breast carcinoma.
Hatice B. Zengin+5 more
doaj +2 more sources
Eccrine sweat gland development and sweat secretion. [PDF]
Cui CY, Schlessinger D.
europepmc +2 more sources
Differential Innervation of Secretory Coils and Ducts in Human Eccrine Sweat Glands
Background: Previous studies demonstrate that eccrine sweat glands are innervated by both cholinergic and adrenergic nerves. However, it is still unknown whether the secretory coils and ducts of eccrine sweat glands are equally innervated by the ...
Zhan Ouyang+4 more
doaj +2 more sources
F-18 FDG PET/CT Imaging of Eccrine Sweat Gland Carcinoma of the Scrotum with Extensive Regional and Distant Metastases [PDF]
Eccrine carcinoma is an extremely rare malignant skin cancer arising from eccrine sweat glands with a high metastatic potential. It mainly occurs in the elderly, with equal incidence in both sexes.
Jin-Suk Kim
doaj +2 more sources
Hailey-Hailey Disease: An Updated Review With a Focus on Therapeutic Mechanisms. [PDF]
ABSTRACT Background Hailey‐Hailey disease (HHD), or familial benign chronic pemphigus, is a rare autosomal dominant genodermatosis characterized by chronic, painful, erythematous, erosive plaques and fissures at sites of friction such as the neck, axilla, groin, and perineum.
Mathur M+4 more
europepmc +2 more sources