Results 121 to 130 of about 2,028 (216)
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and information theory [PDF]
, 2007 BACKGROUND: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targeted treatments.
Ortoleva, Peter J +2 more
core +3 more sources
BioTechniquesExtrachromosomal DNA (ecDNA) are circular DNA structures associated with cancer and drug resistance. One specific type, double minute (DM) chromosomes, has been studied since the 1960s using imaging techniques like cytogenetics and fluorescence ...
Jillann A. Madren +5 more
doaj +1 more source
On the alleged origin of geminiviruses from extrachromosomal DNAs of phytoplasmas
BMC Evolutionary Biology, 2011 Background Several phytoplasmas, wall-less phloem limited plant pathogenic bacteria, have been shown to contain extrachromosomal DNA (EcDNA) molecules encoding a replication associated protein (Rep) similar to that of geminiviruses, a major group of ...
Noris Emanuela +4 more
doaj +1 more source
Plasma extrachromosomal circular DNA as a potential diagnostic biomarker for nodular thyroid disease
Clinical and Translational Medicine, Volume 14, Issue 6, June 2024.
Meng Zhou +19 more
wiley +1 more source
Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis
Journal of InflammationBackground Rheumatoid arthritis (RA) is associated with a high concentration of extracellular DNA (ecDNA). This could be a consequence of the inflammation, but the ecDNA could also be involved in the unknown etiopathogenesis of RA.
Kristína Macáková +9 more
doaj +1 more source
EPCO-14. MULTIFACETED TRANSCRIPTOMIC AND PROTEOMIC ANALYSES IDENTIFIED PUTATIVE ALTERNATIVE SPLICING-DERIVED CELL SURFACE ANTIGENS IN GLIOMA [PDF]
, 2021 BACKGROUND To develop effective immunotherapy for gliomas, it is crucial to expand the repertoire of targetable antigens. Recent studies have suggested that alternative splicing (AS), or its deriving tumor-specific junctions (“neojunctions”), could ...
Costello, Joseph +11 more
core
Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer. [PDF]
Nat CommunDeciphering the structural variation across tumour genomes is crucial to determine the events driving tumour progression and better understand tumour adaptation and evolution.
Ewing A +39 more
europepmc +3 more sources