Results 141 to 150 of about 2,028 (216)

Faculty Opinions recommendation of Circular ecDNA promotes accessible chromatin and high oncogene expression.

, 2019
Yamini Dalal, Ganesan Arunkumar
openalex   +2 more sources

Extrachromosomal Circular DNA: Current Knowledge and Implications for CNS Aging and Neurodegeneration [PDF]

, 2020
Ain, Quratul, Kretz, Alexandra, Schmeer, Christian, Wengerodt, Diane, Witte, Otto W.   +4 more
core   +1 more source

HPV ecDNA in OPSCC AA images

, 2021
Jens Luebeck
openalex   +4 more sources

3C methods in cancer research: recent advances and future prospects

Experimental and Molecular Medicine
In recent years, Hi-C technology has revolutionized cancer research by elucidating the mystery of three-dimensional chromatin organization and its role in gene regulation.
Insoo Yoon, Uijin Kim, Kyung Oh Jung, Yousuk Song, Taesoo Park, Dong-Sung Lee   +5 more
doaj   +1 more source

EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA

iScience, 2019
Summary: Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression.
Utkrisht Rajkumar, Kristen Turner, Jens Luebeck, Viraj Deshpande, Manmohan Chandraker, Paul Mischel, Vineet Bafna   +6 more
doaj  

Aneuploidy and Complex Genomic Rearrangements in Cancer Evolution [PDF]

Mutational processes that alter large genomic regions occur frequently in developing tumors. They range from simple copy number gains and losses to the shattering and reassembly of entire chromosomes.
Baker, Toby M, Tarabichi, Maxime, Van Loo, Peter, Waise, Sara   +3 more
core   +1 more source

The interplay of mutagenesis and extracellular DNA: a new chapter in urothelial cancer research. [PDF]

Mol Biomed
Zhang X, Li Y, Long X.
europepmc   +1 more source

Reviewer #1 (Public Review): Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors

, 2023
Lin Shen, Jo Se-Young, Luebeck Jens, Chang Howard Y., Sihan Wu, Mischel Paul S., Bafna Vineet   +6 more
openalex   +1 more source

Additional file 1 of ATACAmp: a tool for detecting ecDNA/HSRs from bulk and single-cell ATAC-seq data

, 2023
Hansen Cheng, Wenhao Ma, Kun Wang, Han Chu, Guangchao Bao, Yu Liao, Yawen Yuan, Yixiong Gou, Liting Dong, Jian Yang, Haoyang Cai   +10 more
openalex   +2 more sources

A Standardized Protocol for Sample Preparation for Scanning Electron Microscopy (SEM) to Visualize Extrachromosomal DNA (ecDNA)

bioRxiv, 2023
Jillann A. Madren, Jingting Chen, W. Dennis, Christina G. Ford, Kristen K White, Elizabeth Brunk   +5 more
semanticscholar   +1 more source