Results 151 to 160 of about 2,326 (226)

The Landscape of Extrachromosomal DNA (ecDNA) in the Normal Hematopoiesis and Leukemia Evolution

, 2022
Tiansheng Zeng, Wenhui Huang, Longzhen Cui, Wenjuan Zhang, Qing Lin, Pei Zhu, Junyi Li, Tingting Qian, Cong Deng, Lin Fu   +9 more
openalex   +1 more source

Extrachromosomal Circular DNA: Current Knowledge and Implications for CNS Aging and Neurodegeneration [PDF]

, 2020
Ain, Quratul, Kretz, Alexandra, Schmeer, Christian, Wengerodt, Diane, Witte, Otto W.   +4 more
core   +1 more source

Genetic elements promote retention of extrachromosomal DNA in cancer cells. [PDF]

Nature
Sankar V, Hung KL, Gnanasekar A, Wong IT, Shi Q, Kraft K, Jones MG, He BJ, Yan X, Belk JA, Liu KJ, Agarwal S, Wang SK, Henssen AG, Mischel PS, Chang HY.   +15 more
europepmc   +2 more sources

Rearrangement signature visualization for each amplicon containing ecDNA detected in patients with ESCC.

Mingjun Li (178925), Lei Li (29537), Xizi Wang (838412), Yanwei Zhao (1725145), Peina Du (5672948), Wei Wang (17594), Zhenxing Wang (201180), Yadong Wang (82064), Yanxing Sheng (9539585), Mingliang Gu (159631), Xiaodong Jia (783460)   +10 more
openalex   +1 more source

Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability [PDF]

Chromothripsis is a frequent form of genome instability, whereby a presumably single catastrophic event generates extensive genomic rearrangements of one or multiple chromosome(s). However, little is known about the heterogeneity of chromothripsis across
Parra, R. Gonzalo, Przybilla, Moritz J., Simovic Lorenz, Milena, Smirnov, Petr, Susak, Hana   +4 more
core  

Mitotic chromatin compaction tethers extrachromosomal DNA to chromosomes and prevents their mis-segregation into micronuclei. [PDF]

J Biol Chem
Yang LM.
europepmc   +1 more source

Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D. [PDF]

Nat Commun
Chowdhury B, Zhu K, Li C, Alsing J, Luebeck J, Stefanova ME, Chapman OS, Kraft K, Zhang S, Lim JYS, Xie Y, Kim YJ, Wu S, Chavez L, Nir G, Henssen AG, Mischel PS, Chang HY, Bafna V.   +18 more
europepmc   +1 more source

ecDNA cargo gene modeling

, 2023
Shixiang Wang, Qi Zhao
openalex   +2 more sources

Machine learning identified extrachromosomal DNA-related 12 gene signatures to predict cancer immunotherapy response. [PDF]

Cancer Cell Int
Ju Y, Zhang J, Deng J, Wu X, Yang H, Tao C, Li X.   +6 more
europepmc   +1 more source

A system-level metastable model of cancer evolution: integrating replication stress, cell cycle deregulation and chromosomal instability. [PDF]

Ann Med
Ma D, Wang J, Chen Y, Yao L, Wei Q, Wu J.   +5 more
europepmc   +1 more source