Results 151 to 160 of about 1,564 (197)

Echinacoside rescues the SHSY5Y neuronal cells from TNFα-induced apoptosis

open access: yesEuropean Journal of Pharmacology, 2004
We investigated the neuroprotective effect of echinacoside, one of the phenylethanoids isolated from the stems of Cistanches salsa, a Chinese herbal medicine, on tumor necrosis factor-alpha (TNFalpha)-induced apoptosis in human neuroblastoma (SHSY5Y ...
Yong Jiang, Min Deng
exaly   +4 more sources

Struktur von Echinacosid / Structure of Echinacoside

open access: yesZeitschrift Fur Naturforschung - Section C Journal of Biosciences, 1982
Abstract The structure of echinacoside, isolated from Echinacea angustifolia D.C. (Asteraceae) roots has been determided by 1H-NMR-and 13C-NMR-spectra to be β-(3′,4′-dihydroxyphenyl)-ethyl-O-α-ʟ-rhamnopyranosyl (1 → 3)-O-β-ᴅ-[β-ᴅ-glucopyranosyl (1 → 6)]-(4-O-caffeoyl)-glucopyranoside (cf. Fig. 1).
Claude Andary, Hans Becker
exaly   +2 more sources
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Phospholipid complex as an approach for bioavailability enhancement of echinacoside

Drug Development and Industrial Pharmacy, 2015
Echinacoside (ECH) has been shown to possess a multitude of pharmacological activities, however, oral administered ECH failed to fulfill its therapeutic potential due to poor absorption and low bioavailability. Thus, there is a pressing need to develop a new oral dosage form to enhance its intestinal absorption and improve bioavailability.The aim of ...
Zhonglin Yang   +2 more
exaly   +3 more sources

Echinacoside Inhibits Glutamate Release by Suppressing Voltage-Dependent Ca2+ Entry and Protein Kinase C in Rat Cerebrocortical Nerve Terminals

open access: yesInternational Journal of Molecular Sciences, 2016
The glutamatergic system may be involved in the effects of neuroprotectant therapies. Echinacoside, a phenylethanoid glycoside extracted from the medicinal Chinese herb Herba Cistanche, has neuroprotective effects.
Tzu-Yu Lin, Su Jane Wang, Shu-Kuei Huang
exaly   +2 more sources

Echinacoside Ameliorates Cyclophosphamide-Induced Bladder Damage in Mice

Journal of Medicinal Food, 2022
Interstitial cystitis (IC) is featured by apoptosis and chronic inflammation in bladder tissue. We aimed to evaluate the effect of echinacoside (ECH), which is known to modulate inflammation and apoptosis on IC using relevant models. We established a mouse model of cystitis using cyclophosphamide (CYP) and treated human urothelium cells (SV-HUC-1) with
Yunpeng, Shao   +4 more
openaire   +2 more sources

Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease

European Journal of Pharmacology, 2007
In the present study, we investigated the neuroprotective effects of echinacoside, a phenylethanoid glycoside extracted from the medicinal Chinese herb Cistanches salsa, against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity.
Xiaoping Pu
exaly   +3 more sources

Antiosteoporotic activity of echinacoside in ovariectomized rats

Phytomedicine, 2013
Echinacoside (ECH), isolated from Cistanche tubulosa (Schrenk) R. Wight stems, has been reported to enhance bone regeneration in MC3T3-E1 cells in vitro. The objectives of this study were to investigate the antiosteoporotic effect of ECH on bone metabolism in the ovariectomized (OVX) rat model of osteoporosis in vivo.Fifty-six aged 6 months female ...
Fei, Li   +6 more
openaire   +2 more sources

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