Results 71 to 80 of about 1,564 (197)

Echinacoside ameliorates the memory impairment and cholinergic deficit induced by amyloid beta peptides via the inhibition of amyloid deposition and toxicology

open access: yes, 2017
This study investigates the role of the amyloid cascade and central neuronal function on the protective effects of echinacoside in amyloid β peptide 1-42 (Aβ 1-42)-treated SH-SY5Y cells and an Aβ 1-42-infused rat.
Young-Ji Shiao   +3 more
core   +1 more source

Impact of Bacterial Fermentation on Phytochemical Profile and Bioactivity of Calendula officinalis and Echinacea purpurea Extracts

open access: yesInternational Journal of Food Science, Volume 2026, Issue 1, 2026.
The increasing consumer attention toward plant‐based products having health‐promoting benefits has drawn attention to medicinal herbs such as Calendula officinalis and Echinacea purpurea, that are abundant in bioactive compounds exhibiting anti‐inflammatory, antimicrobial and antioxidant properties.
Sofia Massaro   +8 more
wiley   +1 more source

Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: A potential use of Echinacea extracts in the prevention of skin photodamage

open access: yes, 1995
The protective effect of caffeoyl derivatives (echinacoside, chlorogenic acid, chicoric acid, cynarine, and caffeic acid, typical constituents of Echinacea species) on the free radical-induced degradation of Type III collagen has been investigated.
G. Aldini   +5 more
core   +1 more source

Research Progress on the Stability and Degradation Mechanism of Cistanche deserticola Active Compounds During Different Maturity, Preservation, and Processing

open access: yesJournal of Food Processing and Preservation, Volume 2026, Issue 1, 2026.
Cistanche deserticola (CD) Y. C. Ma is a well‐known tonic medicinal material, and its clinical value and industrial development are highly dependent on the integrity of core pharmacodynamic components (such as phenylosides and polysaccharides). This article systematically reviews the impact of three key links: harvest maturity, postharvest preservation
Yao Zhang   +7 more
wiley   +1 more source

Shao Di Pa Ning Decoction Attenuates Neuroinflammation in Parkinson’s Disease via PI3K/AKT Signaling Pathway

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Parkinson’s disease (PD) is a neurodegenerative disorder with limited therapeutic options. Shao Di Pa Ning Decoction (SDPND), a traditional Chinese medicine (TCM) compound formula for PD, has demonstrated therapeutic efficacy, but its underlying mechanisms remain unclear.
Peng Huang   +13 more
wiley   +1 more source

Study on the mechanism of echinacoside in preventing and treating hypoxic pulmonary hypertension based on proteomic analyses

open access: yesPharmacology Research & Perspectives
Hypoxic pulmonary hypertension (HPH), a chronic condition affecting the cardiopulmonary system, has high mortality. Echinacoside (ECH) is a phenylethanoid glycoside, which is used to ameliorate pulmonary vascular remodeling and pulmonary vasoconstriction
Xiangyun Gai   +5 more
doaj   +1 more source

Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 41, Issue 12, December 2025.
ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SIONFH) is a debilitating orthopedic condition. This study investigated the mechanism of Tanshinone I (TsI) in SIONFH modulating apoptosis in SIONFH via the PI3K/AKT/mTOR pathway. A SIONFH rat model was treated with TsI and a PI3K activator. Bone mineral density (BMD), bone volume/total volume
Qing Su, Jia Chen
wiley   +1 more source

Analysis of highly secondary-metabolite producing roots and flowers of two Echinacea angustifolia DC. var. angustifolia accessions

open access: yes, 2010
Echinacea angustifolia var. angustifolia (Asteraceae) is widely used in the nutraceutical, cosmetic and pharmaceutical markets. Echinacoside, a phenol glycoside, is actually considered the marker compound and it is used for the assessment of quality of
AIELLO N   +9 more
core   +1 more source

Revitalising Aging Oocytes: Echinacoside Restores Mitochondrial Function and Cellular Homeostasis Through Targeting GJA1/SIRT1 Pathway

open access: yesCell Proliferation, Volume 58, Issue 10, October 2025.
ECH protects senescent oocytes by stabilising the cytoskeleton, restoring mitochondrial function, reducing oxidative stress and maintaining cellular homeostasis, primarily through the GJA1/SIRT1 signalling pathway. ABSTRACT As maternal age increases, the decline in oocyte quality emerges as a critical factor contributing to reduced reproductive ...
Liuqing Yang   +13 more
wiley   +1 more source

Effects of Plant Meristem-Cell-Based Cosmetics on Menopausal Skin: Clinical Data and Mechanisms

open access: yesBiomolecules
A randomised open clinical/laboratory study was performed to evaluate the safety and cosmetic efficacy of facial cosmetics for females during the menopausal period.
Liudmila Korkina   +7 more
doaj   +1 more source

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