Results 71 to 80 of about 21,506 (220)

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig, Aya C. Taki, Joseph J. Byrne, Pierre Mesdom, Olivier Blacque, Cécile Häberli, Trix Zumkehr, Gonzalo Scalese, Leticia Pérez‐Díaz, Dinorah Gambino, Britta Lundström‐Stadelmann, Jennifer Keiser, Robin B. Gasser, Kevin Cariou, Gilles Gasser   +14 more
wiley   +1 more source

Genome-wide transcriptome analysis of Echinococcus multilocularis larvae and germinative cell cultures reveals genes involved in parasite stem cell function

Frontiers in Cellular and Infection Microbiology
The lethal zoonosis alveolar echinococcosis is caused by tumour-like growth of the metacestode stage of the tapeworm Echinococcus multilocularis within host organs.
Michaela Herz, Magdalena Zarowiecki, Leonie Wessels, Katharina Pätzel, Ruth Herrmann, Christiane Braun, Nancy Holroyd, Thomas Huckvale, Monika Bergmann, Markus Spiliotis, Uriel Koziol, Uriel Koziol, Matthew Berriman, Klaus Brehm   +13 more
doaj   +1 more source

microRNA-125b-5p is a promising novel plasma biomarker for alveolar echinococcosis in patients from the southern province of Qinghai

BMC Infectious Diseases, 2021
Background Alveolar echinococcosis (AE) is caused by parasitic infection by Echinococcus multilocularis. Its diagnosis is usually based on clinical symptoms, ultrasound, and other imaging methods.
Cao Deping, Jiang Bofan, Zhang Yaogang, Pang Mingquan   +3 more
doaj   +1 more source

IL‐33/ST2 Signaling Sustains Hepato‐Intestinal Homeostasis by Orchestrating Vascular Surveillance and Immune Regulatory Circuits During Experimental Trypanosoma cruzi Infection

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Impairment of hepato‐intestinal homeostasis triggered by ST2 deficiency during T. cruzi infection. Within the splenic compartment, immune dysregulation is marked by a robust pro‐inflammatory polarization of the T‐cell landscape. In the liver, ST2 deficiency is associated with hepatocellular injury, increased parasite burden, and hyperalbuminemia ...
Marcelo Eduardo Cardozo, Tatyane Martins Cirilo, José Bryan da Rocha Rihs, Jorge Lucas Nascimento Souza, Isabela de Brito Duval, Ana Rafaela Antunes‐Porto, Luisa Vitor Braga do Amaral, Fernando Bento Rodrigues Oliveira, Mayra Fernanda Ricci, Laura Lis de Oliveira Santos, Lívia Fernanda Dias Santana, Luiza Pinheiro Silva, Chiara Cássia Oliveira Amorim, Gabriela Gomes Monteiro Lemos, Getulío Mota e Silva Junior, Izabela da Silva Oliveira, Marina Possa dos Reys, Ana Laura Grossi de Oliveira, Geovanni Dantas Cassali, Luisa Mourão Dias Magalhães, Lilian Lacerda Bueno, Fabiana Simão Machado, Ricardo Toshio Fujiwara   +22 more
wiley   +1 more source

Future Projection of Cystic Echinococcosis in Iran to 2040: A Secondary Analysis Based on Global Burden of Disease (2021)

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Hydatid cyst disease caused by Echinococcus granulosus poses a major zoonotic threat in Iran, especially in rural and pastoral areas. It causes considerable public health and economic costs due to high treatment expenses, decreased livestock productivity, and carcass condemnation. Methods We applied the illness‐death model (
Behrooz Ahmadi, Meysam Olfatifar, Milad Badri, Mohammad Reza Ghadir   +3 more
wiley   +1 more source

[Vaccination against echinococcosis (?)].

, 2005
Two species of the genus Echinococcus occur sympatrically in central Europe, namely Echinococcus multilocularis, the causative agent of alveolar echinococcosis (AE), and E. granulosus, resulting in cystic echinococcosis (CE) in humans.
Gottstein, Bruno
core   +1 more source

Large Hydatid Cyst in the Cardiac Interventricular Septum: A Rare Case Report and Literature Review

Journal of Clinical Ultrasound, Volume 54, Issue 6, Page 1538-1542, July/August 2026.
Hydatid disease is a parasitic disease with a high incidence in pastoral areas in Tibet. The heart is an uncommon location of echinococcosis, and involvement of the interventricular septum is even rarer. This disease can remain asymptomatic for a long time, but may result in cardiac tamponade and sudden death.
Lin Gao, Yixiu Zhang, Xiao Yang
wiley   +1 more source

Anatomical-Based Imaging of Cystic Echinococcosis and Review of the Current Literature

, 2022
Echinococcosis is a zoonosis caused by cestodes of the genus Echinococcus. This serious disease continues to be an important public health problem as it is endemic in many parts of the world.
Mustafa Yesilyurt, Veysel Esdur, Esdur, Veysel, Yesilyurt, Mustafa   +3 more
core   +1 more source

Status of Human Echinococcosis in Western Mongolia

Central Asian Journal of Medical Sciences, 2019
Objective: The purpose of this study was to identify cases of human echinococcosis in the Bayan-Ulgii, Khovd provinces, to determine their WHO classification by ultrasound and to identify the haplotype in surgically cysts removed.
Temuulen Dorjsuren, Giimaa Narantsogt, Munkhbaatar Davgasumberel, Mandukhai Ganbat, Ganzorig Sumiya, Boldbaatar Damdinsuren, Uranchimeg Tsevelvaanchig, Chinchuluun Boldbaatar, Jambaldorj Jamiyansuren, Sergelen Orgoi, Tsendjav Ayushkhuu, Javkhlantur Bayarlakh, Ishdorj Tseden-Ish, Ganbat Ochir, Gurbadam Agvaandaram, Unursaikhan Ulaankhuu   +15 more
doaj   +1 more source

TTK Overexpression: A Negative Prognostic Biomarker in Anaplastic Thyroid Carcinoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Given threonine and tyrosine kinase (TTK)'s oncogenic role in various cancers and its understudied status in thyroid cancer, this study investigates TTK expression in thyroid lesions to assess its diagnostic and therapeutic potential. Methods We analyzed differential TTK expression levels using public datasets (n = 143) and clinical
Yan Guo, Zhidong Sun, Xiao Liu, Xianni Liu, Haiwen Chen, Menglan Zhang, Weibo Mao, Yuan Cao   +7 more
wiley   +1 more source