Results 1 to 10 of about 26,764 (256)

Echinococcus multilocularis and Echinococcus shiquicus in a small mammal community on the eastern Tibetan Plateau: host species composition, molecular prevalence, and epidemiological implications [PDF]

Parasites & Vectors, 2018
Background The eastern part of the Tibetan Plateau is now recognized as an endemic region with the highest reported human infection rates in the world of human alveolar echinococcosis (AE) caused by Echinococcus multilocularis.
Xu Wang, Jiayu Liu, Qingqiu Zuo, Zhiqiang Mu, Xiaodong Weng, Xiaohui Sun, Junyao Wang, Belgees Boufana, Philip S. Craig, Patrick Giraudoux, Francis Raoul, Zhenghuan Wang   +11 more
doaj   +7 more sources

Transplantation of adipose-derived stem cells ameliorates Echinococcus multilocularis-induced liver fibrosis in mice.

PLoS Neglected Tropical Diseases, 2022
BackgroundAlveolar echinococcosis (AE) can cause severe liver fibrosis and could be fatal if left untreated. Currently, there are no effective therapeutic options for AE-induced liver fibrosis. In view of the therapeutic potential of adipose-derived stem
Ning Yang, Wenmei Ma, Ying Ke, Hui Liu, Jin Chu, Li Sun, Guodong Lü, Xiaojuan Bi, Renyong Lin   +8 more
doaj   +2 more sources

Design of a novel EmTSP-3 and EmTIP based multi-epitope vaccine against Echinococcus multilocularis infection [PDF]

Frontiers in Immunology
BackgroundCurrent treatments and prevention strategies for echinococcosis are inadequate. Recent advancements in molecular vaccine development show promise against Echinococcus granulosus; however, Echinococcus multilocularis remains a challenge. A Multi-
Yichen Fan, Yueyue He, Yujiao Li, Zhengwei Yin, Juan Shi, Tingting Tian, Kaiyu Shang, Huidong Shi, Fengbo Zhang, Fengbo Zhang, Hao Wen   +10 more
doaj   +2 more sources

Structural changes and expression of hepatic fibrosis-related proteins in coculture of Echinococcus multilocularis protoscoleces and human hepatic stellate cells

Parasites & Vectors, 2021
Background Echinococcus multilocularis is the causative agent of human hepatic alveolar echinococcosis (AE). AE can cause damage to several organs, primarily the liver, and have severe outcomes, such as hepatic failure and encephalopathy.
Deping Cao, Emad Shamsan, Bofan Jiang, Haining Fan, Yaogang Zhang, Mustafa Abdo Saif Dehwah   +5 more
doaj   +2 more sources

Echinococcus multilocularis and Echinococcus granulosus in canines in North-Khorasan Province, northeastern Iran, identified using morphology and genetic characterization of mitochondrial DNA

Parasites & Vectors, 2019
Background Canids are definitive hosts of Echinococcus multilocularis and Echinococcus granulosus. This study aimed to survey these two Echinococcus species in canids of North-Khorasan Province, northeastern Iran, using morphological criteria and genetic
Zahra Heidari, Mitra Sharbatkhori, Iraj Mobedi, Seyed Hossein Mirhendi, Bahram Nikmanesh, Meysam Sharifdini, Mehdi Mohebali, Zabihollah Zarei, Kourosh Arzamani, Eshrat Beigom Kia   +9 more
doaj   +2 more sources

Molecular characterization of human Echinococcus isolates and the first report of E. canadensis (G6/G7) and E. multilocularis from the Punjab Province of Pakistan using sequence analysis

BMC Infectious Diseases, 2020
Background Echinococcosis is a zoonotic parasitic disease causing serious health problems in both humans and animals in different endemic regions across the world.
Aisha Khan, Haroon Ahmed, Sami Simsek, Hua Liu, Jianhai Yin, Ying Wang, Yujuan Shen, Jianping Cao   +7 more
doaj   +2 more sources

High PD-1 and CTLA-4 expression correlates with host immune suppression in patients and a mouse model infected with Echinococcus multilocularis [PDF]

Parasites & Vectors
Background Alveolar echinococcosis (AE), a fatal disease caused by Echinococcus multilocularis, often affects the liver, with tumor-like growth. However, the mechanism by which E. multilocularis evades host immune surveillance remains unclear. Methods We
Ting Sun, Yi Yang, Yiwen Qiu, Tao Wang, Ming Yang, Shu Shen, Wentao Wang   +6 more
doaj   +2 more sources

Foxp3 ⁺ T Regulatory Cells as a Potential Target for Immunotherapy against Primary Infection with Echinococcus multilocularis Eggs [PDF]

Infection and Immunity, 2018
Alveolar echinococcosis (AE) is a lethal disease caused by infection with the metacestode stage of the helminth Echinococcus multilocularis, which develops into a tumorlike mass in susceptible intermediate hosts.
Junhua Wang, Rita Cardoso, Nelson Marreros, Norbert Müller, Britta Lundström‐Stadelmann, Myriam Siffert, Dominique A. Vuitton, Franck Boué, Renyong Lin, Hao Wen, Bruno Gottstein   +10 more
openalex   +2 more sources

Echinococcus multilocularis in Northern Hungary [PDF]

Emerging Infectious Diseases, 2004
Tamás Sréter, Zoltán Széll, Zsuzsanna Sréter-Lancz, István Varga   +3 more
doaj   +2 more sources

A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice

Frontiers in Immunology, 2023
Introduction The objective of this study is to construct a multi-epitope vaccine GILE containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) infection based on the dominant epitopes of E. multilocularis EMY162, LAP,
P. Zhou, Z. Zhou, Meiduo Huayu, Lei Wang, Lin Feng, Yang Xiao, Y. Dai, M. Xin, Feng Tang, Runle Li   +9 more
semanticscholar   +1 more source