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Frontiers in ImmunologyBackgroundCurrent treatments and prevention strategies for echinococcosis are inadequate. Recent advancements in molecular vaccine development show promise against Echinococcus granulosus; however, Echinococcus multilocularis remains a challenge. A Multi-
Fengbo Zhang, Hao Wen, Yueyue He
exaly +4 more sources
The spread of Echinococcus multilocularis in the Balkans is facilitated by the golden jackal [PDF]
Frontiers in Veterinary ScienceIntroductionHuman alveolar echinococcosis (AE), caused by the zoonotic tapeworm Echinococcus multilocularis, is an emerging disease in the Balkans. The presence of this tapeworm has been detected in several wildlife species, including the golden jackal ...
Aleksandra Uzelac +10 more
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Frontiers in Immunology, 2021 Echinococcus multilocularis larvae, predominantly located in the liver, cause a tumor-like parasitic disease, alveolar echinococcosis (AE), that is characterized by increased infiltration of various immune cells, including macrophages, around the lesion ...
Hao Wen, Ren-Yong Lin, Shao Ying-Mei
exaly +2 more sources
A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice
Frontiers in Immunology, 2023 Introduction The objective of this study is to construct a multi-epitope vaccine GILE containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) infection based on the dominant epitopes of E. multilocularis EMY162, LAP,
Feng Tang, Li Runle
exaly +2 more sources
Tropical Medicine and Infectious Disease, 2022 Alveolar echinococcosis (AE) is a severe parasitic zoonosis caused by the larval stage of Echinococcus multilocularis. The identification of the antigens eliciting acquired immunity during infection is important for vaccine development against ...
Lujuan Chen +8 more
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First detection of Echinococcus multilocularis in Bosnia and Herzegovina
International Journal for Parasitology: Parasites and Wildlife, 2022 Echinococcus multilocularis has been spreading through Central Eastern Europe but has not yet been reported in Bosnia and Herzegovina (B&H). Recently, this parasite is confirmed in Croatia suggesting the movement of the parasite's distribution limit ...
Jasmin Omeragić +11 more
doaj +2 more sources
PLoS Neglected Tropical Diseases, 2022 BackgroundAlveolar echinococcosis (AE) can cause severe liver fibrosis and could be fatal if left untreated. Currently, there are no effective therapeutic options for AE-induced liver fibrosis. In view of the therapeutic potential of adipose-derived stem
Ning Yang +8 more
doaj +2 more sources
Echinococcus granulosussensu lato and Echinococcus multilocularis: A review.
Research in Veterinary Science, 2020 Echinococcus spp. have a global distribution and are found on every continent except Antarctica. Infections with these parasites are considered extremely serious, contributing to significant morbidity and mortality in addition to substantial economic ...
I. Woolsey, Andrea L. Miller
semanticscholar +5 more sources
Pathogens, 2022 Muskrats (Ondatra zibethicus) are competent intermediate hosts for Echinococcus multilocularis, are frequently infected with this zoonotic cestode, and have even been proposed as a target species to monitor endemicity levels of this parasite.
Thomas Romig +2 more
exaly +2 more sources
Annual assessment of <i>Echinococcus multilocularis</i> surveillance reports submitted in 2026 in the context of Commission Delegated Regulation (EU) 2018/772. [PDF]
EFSA JAbstract This report comprises the 16th assessment of the Echinococcus multilocularis surveillance scientific reports, provided by Finland, Ireland, United Kingdom (Northern Ireland) and Norway on their respective surveillance programmes. Every year since 2012, EFSA presents the assessment to the European Commission (EC) in which the sampling strategy,
European Food Safety Authority (EFSA) +2 more
europepmc +2 more sources