Comparative development of Echinococcus multilocularis in its definitive hosts [PDF]
, 2006 R. C. A. Thompson +3 more
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Cloning and characterization of emp53 from Echinococcus multilocularis [PDF]
, 2015 泡状棘球蚴病(Alveolarechinococcosis，AE)是由棘球绦虫属的多房棘球绦虫(Echinococcusmulticularia，Em)幼虫寄生所致的人畜共患寄生虫病，该病被认为是最致命的蠕虫感染病。泡状棘球蚴在宿主体内生长就必须存在一套防御系统来抵御氧化损伤、维持基因组稳定以及细胞凋亡，肿瘤抑制基因p53被誉为“基因组的卫士”，在应对一系列的刺激和损伤时起了非常重要的作用。 尽管p53在细胞的增殖、分化或凋亡中具有重要的作用，但是到目前为止在寄生蠕虫领域还没有p53相关蛋白的研究报道 ...
朱山
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Genetic structuring and differentiation of Echinococcus multilocularis in Slovakia assessed by sequencing and isoenzyme studies [PDF]
, 2006 Viliam Šnábel +8 more
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Echinococcus multilocularis metacestode metabolites contain a cysteine protease that digests eotaxin, a CC pro-inflammatory chemokine [PDF]
, 2018 In many helminthic infections, eotaxin, a CC-chemokine, triggers the mobilization of eosinophils, thus, contributing to an elevated blood and periparasitic eosinophil level.
Gottstein, B., Mejri, N.
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Occurrence of Echinococcus multilocularis in red foxes from the Carpathian regions of Slovakia and Poland [PDF]
, 2006 K. Reiterová +6 more
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Effects of inhibitor targeting the EGFR/MEK signaling pathway on the growth and development of Echinococcus multilocularis and its molecular mechanism [PDF]
, 2016 泡状棘球蚴病(Alveolarechinococcosis，AE)是由泡状棘球绦虫(Echinococcusmulticularis，Em)幼虫引起的一种致命性的人畜共患寄生虫病。目前对于泡球蚴病的治疗方法十分有限，寻找新型药物靶点十分必要。EGF/EGFR信号通路调控细胞的多种生命活动包括增殖、分化、迁移等，本文在实验室前期研究的基础上，探讨了小分子抑制剂通过对泡球蚴EGF/EGFR介导信号通路作用，对泡球蚴生长发育的影响及其机制。 本文对EGFR抑制剂CI-1033 ...
李秀
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Echinococcus multilocularis in Belgium: Prevalence in red foxes (Vulpes vulpes) and in different species of potential intermediate hosts [PDF]
, 2008 R. Hanosset +4 more
openalex +1 more source
The role of EGFR/ERK signaling for the self-renewal of germinative cells of Echinococcus multilocularis and its molecular mechanism [PDF]
, 2016 多房棘球绦虫（Echinococcusmultilocularis，Em）中绦期幼虫(泡球蚴)在人体内以类似肿瘤的方式进行不断的增殖发育，引发严重的人兽共患泡球蚴病（Alveolarechinococcosis，AE）。泡球蚴不断增殖发育的基础是其生发细胞的自我更新和分化能力，这一特性类似于干细胞。表皮生长因子受体（EGFR）介导的EGFR/ERK信号通路是调控各种干细胞自我更新的主要通路之一，在进化上具有高度的保守性。 本文利用RealtimePCR、WesternBlot、免疫组化荧光和EdU ...
戴梦雅
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