Results 61 to 70 of about 26,814 (299)

Purine metabolism in Echinococcus multilocularis

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 1998
The activities of the enzymes in Echinococcus multilocularis metacestodes involved in purine salvage were studied by HPLC. As in most parasites, this cestode relies entirely on salvage of preformed bases and nucleosides for its purine requirement. Therefore, these enzymes may be targets for drugs in the chemotherapeutic treatment of diseases caused by ...
Anne-Françoise Pétavy, Marie-Elisabeth Sarciron, S Suchail   +2 more
openaire   +4 more sources

Observations on the Development of Echinococcus multilocularis in Cats [PDF]

Journal of Parasitology, 2003
The development of a European isolate of Echinococcus multilocularis was compared in cats and dogs at the end of the prepatent period. Echinococcus multilocularis established in all dogs and cats, but worm recovery was significantly greater from dogs than from cats.
Thompson, R.C.A., Deplazes, P., Eckert, J.   +2 more
openaire   +3 more sources

Echinococcus multilocularisin Dogs, Japan

Emerging Infectious Diseases, 2006
To the Editor: Alveolar echinococcosis in humans is endemic in Japan; however, the causal agent, Echinococcus multilocularis, has been restricted to the northernmost insular prefecture of Hokkaido, where the Tsugaru Strait acts as a natural physical barrier against migration to the mainland. Two E.
Masanori Kawanaka, Hiromu Sugiyama, Kyoko Arakawa, Yasuyuki Morishima   +3 more
openaire   +4 more sources

Revisiting the Phylogenetic History of Helminths Through Genomics, the Case of the New Echinococcus oligarthrus Genome

Frontiers in Genetics, 2019
The first parasitic helminth genome sequence was published in 2007; since then, only ∼200 genomes have become available, most of them being draft assemblies.
Lucas L. Maldonado, Juan Pablo Arrabal, Mara Cecilia Rosenzvit, Guilherme Corrêa De Oliveira, Laura Kamenetzky   +4 more
doaj   +1 more source

Long-term (35 years) cryopreservation of Echinococcus multilocularis metacestodes

Parasitology, 2020
The metacestode of Echinococcus multilocularis is the etiological agent of alveolar echinococcosis. The metacestode stage used for research is maintained in rodents by serial passages. In order to determine whether cryopreservation of E.
Teivi Laurimäe, P. A. Kronenberg, C. A. Alvarez Rojas, T. Ramp, J. Eckert, P. Deplazes   +5 more
semanticscholar   +1 more source

Immunohistological detection of small particles of Echinococcus multilocularis and Echinococcus granulosus in lymph nodes is associated with enlarged lymph nodes in alveolar and cystic echinococcosis

PLoS Neglected Tropical Diseases, 2020
Background Alveolar (AE) and cystic echinococcosis (CE) in humans are caused by the metacestode of the tapeworms Echinococcus multilocularis and Echinococcus granulosus sensu lato (s.l.).
Johannes Grimm, J. Nell, A. Hillenbrand, D. Henne-Bruns, J. Schmidberger, W. Kratzer, B. Gruener, T. Graeter, M. Reinehr, A. Weber, P. Deplazes, P. Möller, Annika Beck, T. Barth   +13 more
semanticscholar   +1 more source

Wrapping the alpha-crystallin domain fold in a chaperone assembly [PDF]

, 2005
Small heat shock proteins (sHsps) are oligomers that perform a protective function by binding denatured proteins. Although ubiquitous, they are of variable sequence except for a C-terminal similar to 90-residue "alpha-crystallin domain".
Basha, Basha, Benitez, Benndorf, Bova, Brunger, Bullard, Cashikar, Chen, Christine Slingsby, De Jong, De La Fortelle, Ding, Doublié, Eddy, Ehrnsperger, Evans, French, Fu, Giese, Guido Kappé, Haslbeck, Haslbeck, Head, Heger, Horwitz, Hsu, Irobi, Kappe, Kappé, Kim, Kim, Laskowski, Lee, Leslie, Lindner, MacRae, Mao, McManus, McRee, Merckelbach, Mogk, Mounier, Nene, Orengo, Perng, Rekas, Robin Stamler, Schneider, Sobott, Stromer, Studer, Theriault, Valdez, Van Montfort, van Montfort, Wilbert Boelens, Zourlidou   +57 more
core   +1 more source

Application of target repositioning and in silico screening to exploit fatty acid binding proteins (FABPs) from Echinococcus multilocularis as possible drug targets

Journal of Computer-Aided Molecular Design, 2020
Fatty acid binding proteins (FABPs) are small intracellular proteins that reversibly bind fatty acids and other hydrophobic ligands. In cestodes, due to their inability to synthesise fatty acids and cholesterol de novo, FABPs, together with other lipid ...
Julián A. Bélgamo, Lucas N. Alberca, J. Pórfido, Franco N. Caram Romero, Santiago Rodriguez, A. Talevi, B. Córsico, G. R. Franchini   +7 more
semanticscholar   +1 more source

Extracellular non-coding RNA signatures of the metacestode stage of Echinococcus multilocularis

PLoS Neglected Tropical Diseases, 2020
Extracellular RNAs (ex-RNAs) are secreted by cells through different means that may involve association with proteins, lipoproteins or extracellular vesicles (EV).
M. Ancarola, G. Lichtenstein, Johannes Herbig, N. Holroyd, M. Mariconti, E. Brunetti, M. Berriman, Krystyna Albrecht, A. Marcilla, M. Rosenzvit, L. Kamenetzky, K. Brehm, M. Cucher   +12 more
semanticscholar   +1 more source

Landscape and climatic characteristics associated with human alveolar echinococcosis in France, 1982 to 2007 , the FrancEchino network [PDF]

, 2015
International audience, the FrancEchino network. Landscape and climatic characteristics associated with human alveolar echinococcosis in France, 1982 to 2007. Euro Surveill. 2015;20(18):pii=21118. Available online: Human alveolar echinococcosis (AE) is a
A Abergel, A Gerard, B Faucher, collective the FrancEchino network, D A Vuitton, F Grenouillet, J Beytout, J Dumortier, J Gaudart, J Knapp, J Watelet, K Bardonnet, M Piarroux, M Wallon, R Piarroux, S Bresson-Hadni   +15 more
core   +2 more sources