Results 61 to 70 of about 20,858 (254)

Metformin Suppresses Development of the Echinococcus multilocularis Larval Stage by Targeting the TOR Pathway

Antimicrobial Agents and Chemotherapy, 2020
Alveolar echinococcosis (AE) is a severe disease caused by the larval stage of the tapeworm Echinococcus multilocularis. Current chemotherapeutic treatment options based on benzimidazoles are of limited effectiveness, which underlines the need to find ...
Julia A Loos, Valeria A. Dávila, K. Brehm, A. Cumino   +3 more
semanticscholar   +1 more source

Echinococcus multilocularis: First European haplotype identified in the United States: An emerging disease?

Clinical Infectious Diseases, 2020
BACKGROUND Echinococcus multilocularis is one of the most severe and lethal parasitic diseases of humans most often reported in Europe and Asia. Only one previous case has been documented in the contiguous United States from Minnesota in 1977.
L. Polish, B. Pritt, T. Barth, B. Gottstein, Elise M O’Connell, P. Gibson   +5 more
semanticscholar   +1 more source

Extracellular non-coding RNA signatures of the metacestode stage of Echinococcus multilocularis

PLoS Neglected Tropical Diseases, 2020
Extracellular RNAs (ex-RNAs) are secreted by cells through different means that may involve association with proteins, lipoproteins or extracellular vesicles (EV).
M. Ancarola, G. Lichtenstein, Johannes Herbig, N. Holroyd, M. Mariconti, E. Brunetti, M. Berriman, Krystyna Albrecht, A. Marcilla, M. Rosenzvit, L. Kamenetzky, K. Brehm, M. Cucher   +12 more
semanticscholar   +1 more source

Investigation of Echinococcus multilocularis in Environmental Definitive Host Feces in the Asian and the European Parts of Turkey

Frontiers in Veterinary Science, 2018
A study was carried out to investigate the presence of Echinococcus multilocularis in red foxes (Vulpes vulpes) in two regions of Turkey—central Anatolia (in Asia Minor) and Thrace (in the European part of Turkey).
Ali Tümay Gürler, Francesca Gori, Cenk Soner Bölükbas¸, Şinasi Umur, Mustafa Açıcı, Peter Deplazes   +5 more
doaj   +1 more source

Application of target repositioning and in silico screening to exploit fatty acid binding proteins (FABPs) from Echinococcus multilocularis as possible drug targets

Journal of Computer-Aided Molecular Design, 2020
Fatty acid binding proteins (FABPs) are small intracellular proteins that reversibly bind fatty acids and other hydrophobic ligands. In cestodes, due to their inability to synthesise fatty acids and cholesterol de novo, FABPs, together with other lipid ...
Julián A. Bélgamo, Lucas N. Alberca, J. Pórfido, Franco N. Caram Romero, Santiago Rodriguez, A. Talevi, B. Córsico, G. R. Franchini   +7 more
semanticscholar   +1 more source

Variation in prevalence and intensity of macroparasites in moose and their interactions with winter tick load in eastern Canada

Wildlife Biology, EarlyView.
Wild animals are infected with a large diversity and abundance of parasites that can affect their behavior, growth, body condition, and ultimately their survival. Although the adverse effects of parasites and the mechanisms involved in the interactions between a host and its parasites are generally well studied, much less is known about the additive or
Catherine Pouchet, Christopher Fernandez‐Prada, Christian Dussault, Martin Leclerc, Jean‐Pierre Tremblay, Steeve D. Côté   +5 more
wiley   +1 more source

Pasture Types and Echinococcus multilocularis, Tibetan Communities

Emerging Infectious Diseases, 2006
Our study showed that open pastures had more small mammal burrows than fenced pastures in Tibetan pastoralist communities in 2003. This characteristic was linked to a higher prevalence of Echinococcus multilocularis in dogs and indicates that pasture ...
Qian Wang, Dominique A. Vuitton, Yongfu Xiao, Christine M. Budke, Maiza Campos-Ponce, Peter M. Schantz, Francis Raoul, Wen Yang, Philip S. Craig, Patrick Giraudoux   +9 more
doaj   +1 more source

Genetic diversity of Echinococcus multilocularis and Echinococcus granulosus sensu lato in Kyrgyzstan: The A2 haplotype of E. multilocularis is the predominant variant infecting humans

PLoS Neglected Tropical Diseases, 2020
Alveolar and cystic echinococcosis (AE, CE) caused by E. multilocularis and E. granulosus s.l., respectively, are considered emerging zoonotic diseases in Kyrgyzstan with some of the world highest regional incidences.
C. A. Alvarez Rojas, P. A. Kronenberg, Sezdbek Aitbaev, Rakhatbek A. Omorov, K. Abdykerimov, G. Paternoster, B. Müllhaupt, P. Torgerson, P. Deplazes   +8 more
semanticscholar   +1 more source

Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture

Molecular Ecology Resources, EarlyView.
ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou, Andrea Waeschenbach, Roy M. Anderson, Piet Cools, Zeleke Mekonnen, D. Timothy J. Littlewood, Cinzia Cantacessi, Stephen R. Doyle   +7 more
wiley   +1 more source

Retrospective Cross‐Sectional Study of Occupational Infection Risk With Zoonotic Pathogens in Austrian Veterinary Practitioners in the Year 2022

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
• Vaccination rates against rabies and TBEV and accordingly the respective seroprevalence rates exceed 90% among Austrian veterinary practitioners. • The prevalence of antibodies against HEV and the colonisation with MRSA increases with the age of the study participants from 6.2%/6.2% in the youngest age group to 23.3%/21.9% in the oldest group. • MRSA
Tatjana Sattler, Bernhard Benka, Irene Zimpernik, Sarah Pürrer, Karoline Waldner, Georg G. Duscher, Agnes Kuffer‐Rosewick, Jasmin Fertey, Sebastian Ulbert, Friedrich Schmoll   +9 more
wiley   +1 more source