Results 31 to 40 of about 2,171 (219)

Brain Temperature as an Indicator of Cognitive Function in Traumatic Brain Injury Patients

Metabolites, 2023
Whether brain temperature noninvasively extracted by magnetic resonance imaging has a role in identifying brain changes in the later phases of mild to moderate traumatic brain injury (TBI) is not known.
Maho Kitagawa, Kagari Abiko, Sulaiman Sheriff, Andrew A. Maudsley, Xinnan Li, Daisuke Sawamura, Sinyeob Ahn, Khin Khin Tha   +7 more
doaj   +1 more source

Pilot Assessment of Brain Metabolism in Perinatally HIV-Infected Youths Using Accelerated 5D Echo Planar J-Resolved Spectroscopic Imaging. [PDF]

PLoS ONE, 2016
PURPOSE:To measure cerebral metabolite levels in perinatally HIV-infected youths and healthy controls using the accelerated five dimensional (5D) echo planar J-resolved spectroscopic imaging (EP-JRESI) sequence, which is capable of obtaining two ...
Zohaib Iqbal, Neil E Wilson, Margaret A Keller, David E Michalik, Joseph A Church, Karin Nielsen-Saines, Jaime Deville, Raissa Souza, Mary-Lynn Brecht, M Albert Thomas   +9 more
doaj   +1 more source

Automated High-Order Shimming for Neuroimaging Studies

Tomography, 2023
B0 inhomogeneity presents a significant challenge in MRI and MR spectroscopy, particularly at high-field strengths, leading to image distortion, signal loss, and spectral broadening.
Jia Xu, Baolian Yang, Douglas Kelley, Vincent A. Magnotta   +3 more
doaj   +1 more source

Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized ¹³C-Pyruvate MRI

Tomography, 2023
Metabolite-specific echo-planar imaging (EPI) sequences with spectral–spatial (spsp) excitation are commonly used in clinical hyperpolarized [1-13C]pyruvate studies because of their speed, efficiency, and flexibility.
Sule I. Sahin, Xiao Ji, Shubhangi Agarwal, Avantika Sinha, Ivina Mali, Jeremy W. Gordon, Mark Mattingly, Sukumar Subramaniam, John Kurhanewicz, Peder E. Z. Larson, Renuka Sriram   +10 more
doaj   +1 more source

Ensemble Learning for Breast Cancer Lesion Classification: A Pilot Validation Using Correlated Spectroscopic Imaging and Diffusion-Weighted Imaging

Metabolites, 2023
The main objective of this work was to evaluate the application of individual and ensemble machine learning models to classify malignant and benign breast masses using features from two-dimensional (2D) correlated spectroscopy spectra extracted from five-
Ajin Joy, Marlene Lin, Melissa Joines, Andres Saucedo, Stephanie Lee-Felker, Jennifer Baker, Aichi Chien, Uzay Emir, Paul M. Macey, M. Albert Thomas   +9 more
doaj   +1 more source

Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone

Frontiers in Oncology, 2021
IntroductionThe pentose phosphate pathway (PPP) is essential for NADPH generation and redox homeostasis in cancer, including glioblastomas.
Georgios Batsios, Céline Taglang, Peng Cao, Anne Marie Gillespie, Chloé Najac, Elavarasan Subramani, David M. Wilson, Robert R. Flavell, Peder E. Z. Larson, Sabrina M. Ronen, Pavithra Viswanath   +10 more
doaj   +1 more source

Design of flyback echo‐planar readout gradients for magnetic resonance spectroscopic imaging [PDF]

Magnetic Resonance in Medicine, 2005
AbstractThe spatial resolution of conventional magnetic resonance spectroscopic imaging‐(MRSI) is typically coarse, mainly due to SNR limitations. The increased signal available with higher field scanners and new array coils now permits higher spatial resolution, but conventional chemical shift imaging (phase encoding) limits the spatial coverage ...
Charles H, Cunningham, Daniel B, Vigneron, Albert P, Chen, Duan, Xu, Sarah J, Nelson, Ralph E, Hurd, Douglas A, Kelley, John M, Pauly   +7 more
openaire   +2 more sources

Echo-Planar J-resolved Spectroscopic Imaging using Dual Read-outs: Implementation and Quantitation of Human Brain Metabolites

Scientific Reports, 2017
Attempts have been made to reduce the total scan time in multi-dimensional J-resolved spectroscopic imaging (JRESI) using an echo-planar (EP) readout gradient, but acquisition duration remains a limitation for routine clinical use in the brain.
Manoj K. Sarma, Rajakumar Nagarajan, Zohaib Iqbal, Paul M. Macey, M. Albert Thomas   +4 more
doaj   +1 more source

Enhanced spectral resolution for correlated spectroscopic imaging using inner-product and covariance transform: a pilot analysis of metabolites and lipids in breast cancer in vivo

Scientific Reports, 2023
Acquisition duration of correlated spectroscopy in vivo can be longer due to a large number of t1 increments along the indirect (F1) dimension. Limited number of t1 increments on the other hand leads to poor spectral resolution along F1.
Ajin Joy, M. Albert Thomas
doaj   +1 more source

Replicability of proton MR spectroscopic imaging findings in mild traumatic brain injury: Implications for clinical applications

NeuroImage: Clinical, 2023
Purpose: Proton magnetic resonance spectroscopy (1H MRS) offers biomarkers of metabolic damage after mild traumatic brain injury (mTBI), but a lack of replicability studies hampers clinical translation.
Anna M. Chen, Teresa Gerhalter, Seena Dehkharghani, Rosemary Peralta, Mia Gajdošík, Martin Gajdošík, Mickael Tordjman, Julia Zabludovsky, Sulaiman Sheriff, Sinyeob Ahn, James S. Babb, Tamara Bushnik, Alejandro Zarate, Jonathan M. Silver, Brian S. Im, Stephen P. Wall, Guillaume Madelin, Ivan I. Kirov   +17 more
doaj   +1 more source