Results 61 to 70 of about 557,914 (307)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Twisted atrioventricular connections in double inlet right ventricle: evaluation by magnetic resonance imaging [PDF]

, 2008
Twisted atrioventricular connections occur almost exclusively in the hearts with biventricular atrioventricular connections. Only one example of double inlet left ventricle has been illustrated in which the axes of the two atrioventricular valves crossed
Anderson, RH, Ho, SY, Kim, TH, Yoo, SJ
core   +1 more source

Disinformation and Echo Chambers: How Disinformation Circulates on Social Media Through Identity-Driven Controversies

Journal of Public Policy & Marketing, 2022
This article investigates how disinformation circulates on social media as adversarial narratives embedded in identity-driven controversies. Empirically, the article reports on the flat Earth echo chamber on YouTube, a controversial group arguing that ...
Carlos Diaz Ruiz, Tomas Nilsson
semanticscholar   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Bridging Echo Chambers? Understanding Political Partisanship through Semantic Network Analysis

Social Media + Society, 2023
In an era of intense partisanship, there is widespread concern that people are self-sorting into separate online communities which are detached from one another.
Jacob Erickson, Bei Yan, Jingyun Huang
semanticscholar   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The Relationship Between Emotional and Other Factors in Information Diffusion

IEEE Access
With the recent proliferation of social media, the spread of disinformation and misinformation has become a global risk. This study analyzes and characterizes the relationship between human emotions and other elements (social bots and echo chambers ...
Shuhei Ippa, Takao Okubo, Masaki Hashimoto   +2 more
doaj   +1 more source

Political content and news are polarized but other content is not in YouTube watch histories

Journal of Quantitative Description: Digital Media, 2023
Research on ideological biases and polarization on social media platforms primarily focuses on news and political content. Non-political content, which is vastly more popular, is often overlooked.
Magdalena Wojcieszak, Rong-Ching (Anna) Chang, Ericka Menchen-Trevino   +2 more
doaj   +1 more source

Strategic tradeoffs in competitor dynamics on adaptive networks [PDF]

, 2017
Recent empirical work highlights the heterogeneity of social competitions such as political campaigns: proponents of some ideologies seek debate and conversation, others create echo chambers. While symmetric and static network structure is typically used
Allard, Antoine, Hébert-Dufresne, Laurent, Libby, Eric, Noël, Pierre-André, Young, Jean-Gabriel   +4 more
core   +2 more sources