Results 91 to 100 of about 98,800 (266)

Clinical Outcomes of the POPCORN Study: Pharmacodynamics of Pre‐Operative PD1 CheckpOint Blockade and Receptor Activator of NF‐κB Ligand (RANKL) Inhibition in Non‐Small Cell Lung Cancer (NSCLC)—A Phase 1B/2 Trial

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern   +11 more
wiley   +1 more source

What Is a Young Life Worth?

open access: yesJACC: Case Reports, 2020
Sharon M. Bates, BS
doaj   +1 more source

The Evolution in Understanding the Physiological Causes of Dyspnoea in Large Hiatal Herniation: A Narrative Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background The symptomatology of large hiatus hernia (LHH) has been historically poorly understood, with cardiorespiratory symptoms caused by LHH being underappreciated by clinicians. This study reports on the mechanisms of dyspnoea in LHH through a historical review of symptoms and evolved physiological literature, discussing likely causation.
Arunan Mahendravarman   +2 more
wiley   +1 more source

Incidence of Childhood Dilated Cardiomyopathy in Sweden From 1991 to 2019: A National Population‐Based Study

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To study the incidence, survival, and mortality of dilated cardiomyopathy (DCM) in children in Sweden, 1991–2019. Methods Hospital records of 0–18‐year‐olds diagnosed with DCM over a 29‐year period were reviewed. The annual sex‐specific incidence rates of DCM were calculated as new disease cases, divided by the average Swedish same‐sex ...
Shalan Fadl   +5 more
wiley   +1 more source

Surgical management of a penetrating cardiac foreign body causing tamponade in a dog: case report

open access: yesAustralian Veterinary Journal, EarlyView.
Background Penetrating cardiac foreign bodies are rare in dogs but can result in life‐threatening complications, including pericardial effusion and cardiac tamponade. Prompt diagnosis, emergency stabilization, and definitive surgical management are essential to achieve a favorable outcome.
RB Abibe   +5 more
wiley   +1 more source

Características ecocardiográficas de la disfunción diastólica en pacientes con tratamiento hemodialítico

open access: yesMedisan
Se realizó una investigación descriptiva y transversal de 64 pacientes (muestra de tamaño calculado) con insuficiencia renal crónica, dependientes del tratamiento hemodialítico, y atendidos en el Servicio de Hemodiálisis del Hospital Provincial Docente ...
Annia Moraga Rodríguez   +4 more
doaj  

Cardiotoxicity of BRAF/MEK inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe   +4 more
wiley   +1 more source

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams   +3 more
wiley   +1 more source

Cardiovascular Autonomic Neuropathy and Indices of Heart Failure in Type 2 Diabetes: The CANCAN Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D). Materials and Methods Two hundred T2D individuals were recruited from two Danish outpatient clinics between 2021–2024. CAN was defined by abnormal cardiovascular autonomic reflex test results.
Jonas R. Schaarup   +7 more
wiley   +1 more source

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