Results 171 to 180 of about 98,800 (266)

The role of vascular risk factors in white matter tract microstructure: a multi‐cohort study in older adults

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Vascular risk factors (VRFs) contribute to white matter microstructural degeneration, but their tract‐specific contributions are unclear. We assessed the independent associations of four major VRFs with white matter microstructure in a large, multi‐cohort study.
James D. LeFevre   +36 more
wiley   +1 more source

A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy   +10 more
wiley   +1 more source

Tricuspid valve repair in infective endocarditis. [PDF]

open access: yesAnn Cardiothorac Surg
Meidrops K   +4 more
europepmc   +1 more source

Clinical and Echocardiographic Outcomes After Implantation of the ALLEGRA Transcatheter Valve Using the Fully Repositionable IMPERIA Delivery System: One‐Year Results of the EMPIRE I Study

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 2, Page 540-547, August 1, 2026.
ABSTRACT Background The EMPIRE I study assessed the early (30 days) safety and efficacy of a new fully repositionable delivery system (IMPERIA) for the commercially available ALLEGRA transcatheter aortic valve in patients with either severe native aortic stenosis or a degenerated surgical bioprosthesis.
José Antonio Baz   +15 more
wiley   +1 more source

A case report of nonrheumatic myocarditis following group G streptococcus pharyngitis. [PDF]

open access: yesRadiol Case Rep
Perkins SJ   +5 more
europepmc   +1 more source

Tacrolimus‐Associated Calcium Pyrophosphate Crystal Arthritis in a Kidney Transplant Recipient: An Underrecognized Condition

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Providers who care for renal transplant recipients should be aware of the possibility of tacrolimus‐associated CPPD in patients who present with arthritis. In the case presented, a delayed diagnosis led to the progression of symptoms and avoidable disability, underscoring the need for greater clinical awareness of this condition within the ...
Matthew Wyke   +5 more
wiley   +1 more source

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi   +5 more
wiley   +1 more source

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