Results 51 to 60 of about 2,850,517 (248)

Initial experience using contrast enhanced real-time three-dimensional exercise stress echocardiography in a low-risk population

Heart International, 2010
Although emerging data support the utility of real-time three-dimensional echocardiography (RT3DE) during dobutamine stress testing, the feasibility of performing contrast enhanced RT3DE during exercise treadmill stress has not been explored.
Smadar Kort, Juan Gamboa, Barbara Blizzard, Laura Buzzanca, Samira Bahrainy, Kathleen Stergiopoulos   +5 more
doaj   +1 more source

Quantitative Assessment of Myocardial Ischemia in Multi-Vessel Coronary Artery Disease by Multimodal Stress Echocardiography with Semi-Supine Bicycle Ergometry

Рациональная фармакотерапия в кардиологии, 2020
Stress echocardiography is a modern widely used method of noninvasive diagnosis of coronary heart disease and stratification of the risk of cardiovascular complications.
S. N. Koretskiy, O. M. Drapkina, F. B. Shukurov, D. K. Vasiliev   +3 more
doaj   +1 more source

ABCDEG Stress Echocardiography in Aortic Stenosis

Diagnostics, 2023
Rest and stress echocardiography (SE) plays a pivotal role in the evaluation of valvular heart disease. The use of SE is recommended in valvular heart disease when there is a mismatch between resting transthoracic echocardiography findings and symptoms ...
Quirino Ciampi, Lauro Cortigiani, Maria Rivadeneira Ruiz, Andrea Barbieri, Fiore Manganelli, Fabio Mori, Maria Grazia D’Alfonso, Francesca Bursi, Bruno Villari   +8 more
doaj   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Left ventricular assessment with artificial intelligence increases the diagnostic accuracy of stress echocardiography. [PDF]

, 2022
To evaluate whether left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS), automatically calculated by artificial intelligence (AI), increases the diagnostic performance of stress echocardiography (SE) for coronary artery disease
Sabharwal, N., Balkhausen, Katrin, Beqiri, Arian, McCourt, Annabelle, Parker, Andrew, Leeson, P., Upton, Ross, Heitner, Stephen, Hawkes, William, Dockerill, Cameron, Sharma, Rajan, Mumith, Angela, Chandrasekaran, B., Kaul, Sanjiv, Woodward, Gary, Yadava, Mrinal, Woodward, W., Sarwar, Rizwan, O'Driscoll, Jamie M, Firoozan, Soroosh, Marciniak, Anna, Kardos, Attila, Augustine, Daniel X   +22 more
core   +1 more source

Parâmetros clínicos e ecocardiográficos associados a baixo índice cronotrópico em pacientes não idosos Clinical and echocardiographic parameters associated with low chronotropic index in non-elderly patients

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: Apesar das inúmeras evidências de aumento da morbimortalidade, a incompetência cronotrópica (IC) ainda não é um diagnóstico rotineiro e bem definido nos protocolos de avaliação cardiológica e sua importância clínica ainda é subestimada ...
Paulo Fernando Carvalho Secundo, Bruno Fernandes de Oliveira Santos, José Alves Secundo Júnior, Joiciane Bárbara da Silva, Adriana Ribeiro de Souza, Gustavo Baptista de Almeida Faro, José Augusto Barreto- Filho, Antônio Carlos Sobral Sousa, Joselina Luzia Menezes Oliveira   +8 more
doaj  

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Diagnostic Test Squatting Stress Echocardiography and Coronary Angiography in Diagnosing Coronary Heart Disease

Majalah Kardiologi Indonesia, 2017
Background: In patients with significant coronary heart disease (CHD), increased preload and afterload during a squat can cause wall motion abnormalities (WMA) which can be detected on echocardiography.
Andy Rahman, Mefri Yanni, Masrul Syafri
doaj   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source