Results 311 to 320 of about 704,143 (399)

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal   +9 more
wiley   +1 more source

Echocardiography assessment of aortic elasticity as a vascular marker in hypertensive vs. healthy individuals. [PDF]

open access: yesSci Rep
Gholipour M   +9 more
europepmc   +1 more source

A new staging system for hereditary transthyretin amyloidosis in the era of specific amyloidosis therapies

open access: yesESC Heart Failure, EarlyView.
The aim of our study was to develop a more accurate staging system for hereditary ATTR patients currently receiving specific treatment. A staging system was created using as criteria: GLS ≤ −11%, NT‐proBNP ≤ 2,000 ng/L, and eGFR ≤ 65 mL/min. We managed to accurately stratify patients into three disease stages, significantly different in terms of ...
Gabriela Neculae   +7 more
wiley   +1 more source

Percutaneous endocardial alginate–hydrogel injection in the treatment of heart failure: First‐in‐human study

open access: yesESC Heart Failure, EarlyView.
Using EndoWings™ and XDROP™, we developed a percutaneous minimally invasive technique for sequential circumferential alginate hydrogel injection into LV free mid‐wall. This human study assessed its safety/feasibility in HFrEF patients, with personalised biomechanical models.
Bo Wang   +13 more
wiley   +1 more source

Infective Endocarditis 19 Months After Transcatheter Ostium Secundum Atrial Septal Defect Closure in a 6-Year-Old. [PDF]

open access: yesJACC Case Rep
Gery C   +6 more
europepmc   +1 more source

Nurse‐coordinated multidisciplinary comprehensive heart failure management programme: A propensity‐matched trial

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Despite therapeutic advancements, the prognosis of heart failure (HF) remains poor, with high rates of mortality and readmission, particularly following a HF exacerbation. This study aimed to evaluate the effects of a nurse‐coordinated multidisciplinary comprehensive HF management programme on HF patients.
Cecilia Miu‐Ching Chan   +13 more
wiley   +1 more source

Ethnic differences in protein biomarkers of peripartum cardiomyopathy: a proteomic study on the EORP cohort

open access: yesESC Heart Failure, EarlyView.
Abstract Aims The diagnosis of peripartum cardiomyopathy (PPCM) is often delayed due to the absence of disease‐specific biomarkers. Recently, serum proteins—QSOX1, adiponectin (ADIPOQ) and ITIH3—have shown potential for improving diagnostic accuracy, especially when used with NT‐proBNP.
Vitaris Kodogo   +13 more
wiley   +1 more source

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