Results 51 to 60 of about 255,581 (267)

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

A rare case of congenital absence of left atrial appendage diagnosed by multimodal imaging

Science Progress
Congenital absence of the left atrial appendage (LAA) is an exceptionally rare cardiac anomaly. We reported a patient in his 60s with symptomatic persistent atrial fibrillation (AF) and no history of cardiac surgery or other diseases.
Chenyu Wang, Jiancheng Han, Zhaoying Wen, Yihua He, Ying Zhao   +4 more
doaj   +1 more source

Value of quantitative analysis of left ventricular systolic function in patients on maintenance hemodialysis based on myocardial work technique

BMC Cardiovascular Disorders, 2021
Background This study aimed to determine the left ventricular (LV) systolic function in patients on maintenance hemodialysis (MHD) using the myocardial work (MW) technique and investigate the clinical value of the MW technique for the quantitative ...
Chang Liu, Yi-Ping Feng, Zi-Ning Yan, Li Fan, Yi-Fei Rui, Ling Cui   +5 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Quantitative evaluation of longitudinal strain in layer-specific myocardium during normal pregnancy in China

Cardiovascular Ultrasound, 2016
Background The myocardial wall of the left ventricle is a complex, multilayered structure and is not homogenous. The aim of this study was to determine longitudinal strain (LS) in the three myocardial layers in normal pregnant women according to ...
Juan Cong, Zhibin Wang, Hong Jin, Wugang Wang, Kun Gong, Yuanyuan Meng, Yong Lee   +6 more
doaj   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

Research Progress of Nerve Injury–Induced Protein 1 in Cardiovascular Diseases

Cardiology Research and Practice
Nerve injury–induced protein 1 (Ninjurin 1) is a cell surface adhesion molecule that contains one extracellular adhesion domain and two transmembrane domains.
Xiaohui Xu, Yuming Mu
doaj   +1 more source

Impaired Right Ventricular Mechanics at Rest and During Exercise Are Associated With Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Impaired right ventricular (RV) function indicates RV involvement in patients with hypertrophic cardiomyopathy (HCM). We aimed to assess RV function at rest and during exercise in HCM patients and to examine the association between impaired RV
Xiao‐Peng Wu, Yi‐Dan Li, Yi‐Dan Wang, Miao Zhang, Wei‐Wei Zhu, Qi‐Zhe Cai, Wei Jiang, Lan‐Lan Sun, Xue‐Yan Ding, Xiao‐Guang Ye, Yun‐Yun Qin, Xiu‐Zhang Lu   +11 more
doaj   +1 more source

Subclinical left ventricular myocardial dysfunction in patients with obstructive sleep apnea syndrome: insights from noninvasive left ventricular myocardial work analysis

BMC Cardiovascular Disorders, 2022
Background Obstructive sleep apnea syndrome (OSAS) is associated with various cardiovascular diseases and has aroused public concern. Early detection for declining myocardial function is of great significance.
Shan Jin, Xueyan Ding, Dichen Guo, Yunyun Qin, Weiwei Zhu, Zhiling Zhao, Xiheng Guo, Yidan Li, Xiuzhang Lu, Qizhe Cai   +9 more
doaj   +1 more source

The Year in Echocardiography

Journal of the American College of Cardiology, 2004
The year in echocardiography has been marked by incremental progress in our understanding of the methodology and potential applications of techniques introduced in the last few years, such as speckle tracking (STE), real-time 3-dimensional echocardiography (RT3DE), and Doppler tissue imaging (DTI).
openaire   +8 more sources