Results 81 to 90 of about 382,724 (313)

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Effect of Performing Real Time Three-Dimensional Transesophageal Echocardiography in Addition to Two-Dimensional Transesophageal Echocardiography on Operator Diagnostic Confidence

, 2011
This study evaluates the effects of performing real time three-dimensional transesophageal echocardiography in addition to conventional two-dimensional transesophageal echocardiography on diagnostic confidence.
Carol Ma, Torres, Silvia, Howard J. Willens, Willens, Howard J, Keith, Karen, Jian Xin Qin, Grossman, Jay R, Hendel, Robert C, Silvia Torres, Robert C. Hendel, Jay R. Grossman, Karen Keith, Mauro Moscucci, Qin, Jian Xin, Ma, Carol, Moscucci, Mauro   +15 more
core   +1 more source

Echocardiography 2020: Toward deciphering the “Rosetta stone” of left ventricular diastolic function

, 2020
In the year 1997, nearly a quarter-century ago, Nishimura and Tajik (J Am Coll Cardiol. 1997;30:8) suggested that Doppler echocardiography was the "Rosetta stone" (a metaphor for decrypting secrets of diastole) of left ventricular diastole, based solely ...
Anatoli Kiotsekoglou, Nanda, Navin C., Samir K. Saha, Saha, Samir Kanti,, Navin C. Nanda, Kiotsekoglou, Anatoli   +5 more
core   +1 more source

Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

Advanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu, Yufei Sun, Xinlei Wu, Haixia Chen, Shaocong Mo, Zichong Li, Yiwei Gong, Xiaoqian Shan, Yuanqi Li, Yaru Guan, Junqi Zhu, Han Yan, Min Du, Feng Wei, Peixin Ou, Ziyi Wang, Chenting Zhang, Lei Xu, Wenju Lu, Jian Wang, Kai Yang   +20 more
wiley   +1 more source

Cardiovascular Magnetic Resonance Deformation Imaging By Feature Tracking For Assessment Of Left And Right Ventricular Structure And Function [PDF]

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorCardiac magnetic resonance (CMR) imaging is the gold standard imaging technique for
Augustine, Daniel
core   +1 more source

Evaluation of left atrial volume and function using single-beat real-time three-dimensional echocardiography in atrial fibrillation patients

BMC Medical Imaging, 2017
Background This study was aimed to evaluate the feasibility and accuracy of real-time three-dimensional echocardiography (RT-3DE) measurement of left atrial (LA) volume and function in comparison with two-dimensional echocardiography (2DE) measurements ...
Qian Zhang, Ju-fang Wang, Qing-qing Dong, Qing Yan, Xiang-hong Luo, Xue-ying Wu, Jian Liu, Ya-ping Sun   +7 more
doaj   +1 more source

Alteration of Surgical Management Following Intraoperative Transesophageal Echocardiography in a Patient With Mobile Left Atrial Thrombi Embolized During Anesthesia

, 2003
This report describes alteration of surgical management in a patient with a large free-floating ball thrombus in the left atrium, which was embolized before sternotomy as demonstrated by intraoperative transesophageal echocardiography.
장병철, 하종원, 곽영란, 정남식   +3 more
core   +1 more source

Targeting Nupr1‐Mediated p53 Mitochondrial Sequestration Alleviates Aortic Dissection by Restoring the Gadd45b‐Dependent Survival Program

Advanced Science, EarlyView.
This study identifies Nupr1 as a crucial stress‐responsive orchestrator driving AD. Under severe stress, Nupr1 massively accumulates within mitochondria to sequester p53, triggering apoptosis and concurrently repressing the Gadd45b‐mediated survival program.
Xi Yang, Ke‐Yuan Chen, Yue Tian, Zong‐Sheng Jiang, Jian Lei, Xing‐Hui Zhuang, Jiang‐Bin Wu, Le‐Le Tang, Hao‐Yu Li, Xiao‐Hui Chen, Yue Wang, Yu‐Mei Li, Zhi‐Huang Qiu, Zi‐Wen Cai, Liang‐Wan Chen   +14 more
wiley   +1 more source

Three-dimensional trans-esophageal echocardiographic evaluation of atrial Septal defects : a pictorial essay [PDF]

, 2011
This pictorial assay illustrates the methodology of evaluating the atrial septal defects by three dimensional transesophageal echocardiography with the help of representative images.
Shrivastava, Sameer, Sharma, Vinay Kumar, Radhakrishnan, Sitaraman   +2 more
core  

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source