Results 51 to 60 of about 78,736 (309)

Pre-Eclampsia and Eclampsia: An Update on the Pharmacological Treatment Applied in Portugal

Journal of Cardiovascular Development and Disease, 2018
Pre-eclampsia and eclampsia are two hypertensive disorders of pregnancy, considered major causes of maternal and perinatal death worldwide. Pre-eclampsia is a multisystemic disease characterized by the development of hypertension after 20 weeks of ...
Gonçalo Miguel Peres, Melissa Mariana, Elisa Cairrão   +2 more
doaj   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

The Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson, Pierre Frémondière, Kaspar Staub, Philipp Mitteroecker, Barbara Fischer, Martin Haeusler, Nicole M. Webb   +6 more
wiley   +1 more source

Effects of sirtuin 1 deficiency on trophoblasts and its implications in the pathogenesis of pre-eclampsia

, 2023
Sirtuin 1 (SIRT1) is mainly localised in syncytiotrophoblasts and cytotrophoblasts, and is involved in pregnancy regulation. However, data on the association between SIRT1 and pre-eclampsia (PE) remains limited.
Ping Du (328871), Ling Chen (25698), Xianping Liu (1657897), Hongbiao Yu (9544280), Ying Xia (222301)   +4 more
core   +1 more source

Higher Circulating Lymphocytes and the Incidence of Pre-eclampsia and Eclampsia

Journal of Pregnancy
Excessive immune activation contributes to the onset of early dysfunction of the maternal-fetal interface, and it is closely linked to the development of pre-eclampsia.
Qiuping Zhao, Rongmei Liu, Hui Chen, Xiaomo Yang, Jiajia Dong, Minfu Bai, MingYang Yu, Zeying Feng, Dingyuan Zeng   +8 more
doaj   +1 more source

Nationwide Temporal Trends in Adverse Pregnancy Outcomes and Treatments in Systemic Lupus Erythematosus Pregnancy Over Two Decades in Sweden

Arthritis &Rheumatology, EarlyView.
Objective This nationwide descriptive study examined temporal trends in adverse pregnancy outcomes (APOs) and treatments in systemic lupus erythematosus (SLE) pregnancies in Sweden over 2003 to 2022. Methods Using nationwide Swedish registers, we identified 1,417 pregnancies of women with prevalent SLE and delivery dates in 2003 to 2022 and matched ...
Ngoc V. Nguyen, Anna Sandström, Annica Dominicus, Elisabet Svenungsson, Karin Hellgren, Julia F. Simard, Elizabeth V. Arkema   +6 more
wiley   +1 more source

Characteristics Symptoms of Imminent Eclampsia: A case Referent Study from a Tertiary Hospital in Tanzania [PDF]

, 2012
\ud \ud Maternal mortality in developing coun- tries is unacceptably high with eclampsia being con- sistently among the top causes. As yet, primary pre- vention of this complication is not possible since causes of pre-eclampsia are largely unknown and ...
France, John, Muganyizi, Projestine S.
core  

FAS gene polymorphisms (rs3740286 and rs4064) were not associated with pre-eclampsia risk [PDF]

Anais da Academia Brasileira de Ciências, 2020
Pre-eclampsia results in real risk and significant impact on indicators related to maternal and child health. The only known treatment is delivery of the fetus and placenta. Despite intensive research, the causes of PE remain to be elucidated.
SARAH C.S.V. TANAKA, IVANIR C. ORLANDO JÚNIOR, ANDREZZA C.C. HORTOLANI, MARIÂNGELA T.R. CINTRA, MARLY A.S. BALARIN, SUELI R. DA SILVA, CRISTINA W. PISSETTI   +6 more
doaj   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) multi-country prospective cohort study.

, 2014
BACKGROUND: Pre-eclampsia/eclampsia are leading causes of maternal mortality and morbidity, particularly in low- and middle- income countries (LMICs). We developed the miniPIERS risk prediction model to provide a simple, evidence-based tool to identify ...
Jennifer A Hutcheon, Haniff Farizah, Jing Li (10611), Haniff, F, Qu, Z, Steyn, DW, D Wilhelm Steyn, Grobman, WA, Hall, David R., Jennifer A. Hutcheon (368523), Annettee Nakimuli (512186), Zulfiqar A. Bhutta (121489), Mariana Widmer (232499), Bhutta Shereen Z., Shereen Z Bhutta, Bhutta, ZA, miniPIERS Study Working Group, Farizah Haniff (512184), Shereen Z. Bhutta (512181), Widmer, M, Bhutta, Shereen Z., Ansermino, J. Mark, Diane Sawchuck (512189), Sawchuck Diane, Steyn, D. Wilhelm, Groen, Henk, Hall, DR, von Dadelszen Peter, Payne, Beth A., Henk Groen, Steyn D. Wilhelm, Nakimuli, A, Widmer, Mariana, Rozina Sikandar, Biryabarema, Christine, von Dadelszen, Peter, D. Wilhelm Steyn (512190), Merialdi, M, Laura A. Magee (512185), Magee Laura A., Qu, Ziguang, Peter von Dadelszen, Zhou Jian, Dadelszen, Peter von, David R. Hall (106818), MiniPIERS Study Working Grp, Sass, Nelson [UNIFESP], Grobman, William A., Widmer Mariana, Hutcheon, Jennifer A., Sikandar Rozina, Bhutta, Zulfiqar A., Rozina Sikandar (512188), Beth A Payne, Biryabarema, C, Annettee Nakimuli, Nakimuli, Annettee, Bhutta Zulfiqar A., Ansermino, JM, Grobman William A., Sikandar, Rozina, Ziguang Qu, Payne Beth A., Zhou, Jian, Henk Groen (444146), Sikandar, R, Zulfiqar A Bhutta, Groen Henk, Jian Zhou (28020), Magee, Laura A., Jian Zhou, Sass Nelson, Groen, Henk; id_orcid, Merialdi Mario, Jing Li, Li Jing, Zhou, J, von Dadelszen, P, Mario Merialdi (164060), William A Grobman, Bhutta, Zulfiqar Ahmed, Sawchuck, Diane, Hutcheon Jennifer A., Mario Merialdi, Payne, BA, Sawchuck, D, Nelson Sass, ?, ?, Hutcheon, JA, Merialdi, Mario, Biryabarema Christine, Hall David R., Ziguang Qu (512187), Nakimuli Annettee, Li, J, J Mark Ansermino, Qu Ziguang, Christine Biryabarema (512182), J. Mark Ansermino (426355), Farizah Haniff, Mariana Widmer, Bhutta, SZ, Beth A. Payne (512180), Haniff, Farizah, David R Hall, Groen, H, Nelson Sass (346028), Ansermino J. Mark, Sultanali, Rozina Sikandar, Li, Jing, Christine Biryabarema, Diane Sawchuck, von Dadelszen, Peter; id_orcid, Sass, Nelson, Sass, N, Peter von Dadelszen (258508), Magee, LA, William A. Grobman (512183), Laura A Magee   +118 more
core   +1 more source

Pre-eclampsia

, 2023
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia have reduced life expectancy, with increased risks of stroke, cardiovascular ...
Nicolaides, Kypros H., Ellen Menkhorst, Wei Zhou, Hyett, Jon A. (R20572), Rolnik, Daniel L., Whitehead, Clare, Costa, Fabricio da Silva, Kaori Koga, Fabricio da Silva Costa, Rossana P. V. Francisco, Evdokia Dimitriadis, Kypros Nicolaides, Estrada-Gutierrez, Guadalupe, Daniel L. Rolnik, Francisco, Rossana P., Zhou, Wei, Clare Whitehead, Guadalupe Estrada-Gutierrez, Koga, Kaori, Francisco, Rossana PV, Nicolaides, Kypros, Rolnik, Daniel L, Dimitriadis, Evdokia, Hyett, Jon, Jon Hyett, Menkhorst, Ellen   +25 more
core   +1 more source