By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li +14 more
wiley +1 more source
Magnetic activities of two contact binaries in quadruple stellar systems. [PDF]
Yang Y, Wang S.
europepmc +1 more source
ToCV‐encoded p22 targets chloroplast plastoglobules (PGs) via directly binding PG structural protein FBN1.1, reducing the size of PG and inhibiting α‐tocopherol biosynthesis via competing with tocopherol cyclase (VTE1). Consequently, the elevated chloroplast ROS not only creates a suitable cellular environment for efficient ToCV infection but also ...
Sijia Liu +8 more
wiley +1 more source
Advantages and limitations of navigation-based multicriteria optimization (MCO) in selectively sparing pharyngeal constrictor muscles in head and neck radiotherapy treatment planning. [PDF]
Howard LK +3 more
europepmc +1 more source
Early events in dengue virus infection inducing cytokine storm: The dynamic interplay of pattern-recognition receptors, inflammasome activation, and biphasic NF-κB and STAT1-dependent inflammatory responses in human mononuclear phagocytes. [PDF]
Valdés-López JF +5 more
europepmc +1 more source
The Role of Orbital Atherectomy for Complex Coronary Calcium Modification: Has It Been Eclipsed? [PDF]
Khullar N, Singh T, O'Kane P, Hinton J.
europepmc +1 more source
Extreme weather variability on hot rocky exoplanet 55 Cancri e explained by magma temperature-cloud feedback. [PDF]
Loftus K, Luo Y, Fan B, Kite ES.
europepmc +1 more source
A dynamic anthropomorphic phantom for end-to-end testing in image- and surface-guided adaptive radiotherapy. [PDF]
Bakhtiari Moghaddam A +18 more
europepmc +1 more source
hADMSC-YTZP seeding improves peri-implant bone repair through increased expression of BMP-2, ALP, and OPG. [PDF]
Rachman A +4 more
europepmc +1 more source

