Results 151 to 160 of about 42,354 (272)

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Pulmonary Artery Intimal Sarcoma Mimicking Pulmonary Embolism: A Case Report. [PDF]

J Belg Soc Radiol
Van Den Berghe T, Mahieu R, Verstraete K.   +2 more
europepmc   +1 more source

Neutron star mass estimates from gamma-ray eclipses in spider millisecond pulsar binaries. [PDF]

Nat Astron, 2023
Clark CJ, Kerr M, Barr ED, Bhattacharyya B, Breton RP, Bruel P, Camilo F, Chen W, Cognard I, Cromartie HT, Deneva J, Dhillon VS, Guillemot L, Kennedy MR, Kramer M, Lyne AG, Sánchez DM, Nieder L, Phillips C, Ransom SM, Ray PS, Roberts MSE, Roy J, Smith DA, Spiewak R, Stappers BW, Tabassum S, Theureau G, Voisin G.   +28 more
europepmc   +1 more source

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source

Assessment of coastal bedrock groundwater quality in Jiaodong Peninsula via extension cloud model and resampling strategy. [PDF]

Sci Rep
Dong W, Zhang B, Hu X, Yang Y, Wang Z, Li B.   +5 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Optimizing water quality index using machine learning: a six-year comparative study in riverine and reservoir systems. [PDF]

Sci Rep
Yuan P, Li H, Yi X, Wang J, Ning C, Xu X, Nong X.   +6 more
europepmc   +1 more source

A binary pulsar in a 53-minute orbit. [PDF]

Nature, 2023
Pan Z, Lu JG, Jiang P, Han JL, Chen HL, Han ZW, Liu K, Qian L, Xu RX, Zhang B, Luo JT, Yan Z, Yang ZL, Zhou DJ, Wang PF, Wang C, Li MH, Zhu M.   +17 more
europepmc   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Diagnoses Live in Relationships: Bedside Sense in the Age of Precision Medicine. [PDF]

Ann Fam Med
Yuan K, Lu H, Zhan H, Chen Y, Zh Y, Wang C.   +5 more
europepmc   +1 more source