Results 71 to 80 of about 18,124 (285)
Extracorporeal life support in pediatric cardiac patients
Frontiers in Pediatrics, 2016 Extracorporeal Life Support (ECLS) is a valuable tool in the management of neonates and older children with severe cardiac or respiratory failure. In this review, we focus on ECLS when used for neonatal and pediatric cardiac disease.
Matteo Di NARDO +5 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Yale journal of biology and medicine, 1999 Using immunohistochemistry at the conventional light, confocal and electron microscopic levels, we have demonstrated that rat stomach ECL cells store histamine and pancreastatin in granules and secretory vesicles, while histidine decarboxylase occurs in the cytosol.
D, Chen +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Extraction of ketamine and dexmedetomidine by extracorporeal life support circuits★
The Journal of ExtraCorporeal TechnologyBackground: Patients supported with extracorporeal life support (ECLS) circuits such as ECMO and CRRT often require high doses of sedatives and analgesics, including ketamine and dexmedetomidine.
Chevalier Andrew +5 more
doaj +1 more source
Late recovery from total lung injury after ECMO support
Egyptian Journal of Critical Care Medicine, 2018 ECMO supports life in the total absence of lung function. Some patients with apparently irreversible lung injury recover completely after months of ECMO support.
Robert H. Bartlett
doaj +1 more source
Biosensors, 2018 We present an animal model used to evaluate the in vivo performance of electrochemical amperometric continuous lactate sensors compared to blood gas instruments.
Alexander Wolf +8 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
The environmental control and life-support system for a lunar base: What drives its design [PDF]
The purpose of this paper is to identify and briefly discuss some of the ground rules and mission scenario details that become drivers of the environmental control and life support (ECLS) system design and of the logistics related to the design.
Hall, John B., Jr., Hypes, Warren D.
core +1 more source
Addressing the challenges of ECMO simulation [PDF]
, 2018 This document is the Accepted Manuscript. The final, definitive version of this paper has been published in Perfusion, May 2018, published by SAGE Publishing, All rights reserved.Introduction/Aim: The patient’s condition and high-risk nature of ...
Ait Hssain, Ali +9 more
core +2 more sources