Results 131 to 140 of about 173,752 (224)
The Level of Social Capital, Innovation and Competitiveness in the Countries of the European Union (EU) [PDF]
, 2014 Hvižďáková, Ivana +1 more
core +1 more source
Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis
Advanced Science, EarlyView.This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun +15 more
wiley +1 more source
Dynamic efficiency of Extended Producer Responsibility (EPR) instruments in a simulation model of industrial dynamics [PDF]
This paper presents an original approach to the impact of extended producer responsibility instruments for waste prevention upon firms\' innovative strategies and market structure.
Eric BROUILLAT (GREThA, CNRS, UMR 5113) +1 more
core
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle [PDF]
, 2010 peer-reviewedSelection based on genetic polymorphisms requires accurate quantification of the effect or association of the polymorphisms with all traits of economic importance. The objective of this study was to estimate, using progeny performance data
Berry, Donagh +5 more
core
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Advanced Science, EarlyView.A green, thermoreversible self‐assembly strategy yields a multifunctional and recyclable supramolecular nanofibrous membrane. Graphene oxide (GO) nanosheet acts as a heterogeneous nucleation‐templating agent, simultaneously modulating the supramolecular crystal packing while tailoring the nanofibrous architecture for elite performance.
Wenjing Sun +6 more
wiley +1 more source
Green Growth in the OECD: State of the Art
Theory, Methodology, Practice, 2014 The concept and initiative of green (world) economy but especially the greening of industry is not new. It appeared 20 years ago at the Rio World Summit, and since that time it has been discussed constantly, integrating more new and complex approaches ...
Klára Szita Tóth
doaj
Species Dependent Toxicity Comparison Outcome
Advanced Science, EarlyView.By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao +7 more
wiley +1 more source
Advanced Science, EarlyView.The adsorption of AsV on akaganeite nanorods was found to provide a magnetic signature. A change in the surface spin order gave rise to a second peak in the zero‐field cooled curve. AsIII adsorption does not provide any change in the magnetic behavior of the sorbent.
Marco Sanna Angotzi +11 more
wiley +1 more source