The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang +7 more
wiley +1 more source
EF-Feddr: communication-efficient federated learning with Douglas-Rachford splitting and error feedback. [PDF]
Xue J, Wang C.
europepmc +1 more source
Inspired by spider silk, a bio‐inspired polyamide elastomer with a dynamic physical cross‐linking network is developed. Mimicking the rigid β‐sheet crystals and sacrificial hydrogen bonds of silk, the material achieves an exceptional balance of strength and toughness.
Bo Yang +12 more
wiley +1 more source
Eco-optimized RP-HPLC method for chiral tazobactam and piperacillin drugs: integration with Box-Behnken design and multi-sustainability tools. [PDF]
Al-Wasidi AS +5 more
europepmc +1 more source
This work reports a strategy of engineering charge‐assisted hydrogen bonds to tailor charge transfer channels in HOFs, significantly improving their performance in photocatalytic H2O2 production. ABSTRACT The production of H2O2 via artificial photosynthesis is often limited by inefficient charge‐carrier separation, causing significant charge ...
Yajun Zhao +7 more
wiley +1 more source
Integrated 3D Printing of Liquid Metal and Elastomer for Soft Robots and Electronics. [PDF]
Song X +5 more
europepmc +1 more source
Reinforcing Oxygen Activation of Spinel Oxide via Mn─O Covalency Engineering for VOCs Oxidation
A MnCo spinel catalyst with weakened Mn─O covalency was synthesized via a hard‐template method. The reduced Mn─O covalency facilitates localized electron redistribution, promoting the activation of both molecular oxygen and lattice oxygen, and thereby enabling the efficient and complete oxidation of VOCs (ethyl acetate, toluene, and propane).
Gan Li +8 more
wiley +1 more source
Evaluating the Effectiveness of a Creative Arts and Philosophical Inquiry Intervention Rooted in Self-Determination Theory to Promote Adaptive Coping with Eco-Anxiety among Elementary School Children: A Pilot Randomized Cluster Trial. [PDF]
Léger-Goodes T +6 more
europepmc +1 more source
A bipolar CNT@COF core–shell heterostructure cathode constructed via synergistic molecular and microstructural engineering enables rapid electron/ion transport and efficient utilization of electroactive groups for high–performance lithium–organic batteries. ABSTRACT Covalent organic frameworks (COFs) with tunable molecular structures and ordered porous
Yalong Jiang +6 more
wiley +1 more source
Exploring the pathways between physical activity, love for nature and eco-friendly behavior in children. [PDF]
Theodorakis Y +6 more
europepmc +1 more source

