Results 91 to 100 of about 907,299 (242)

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Cultural and educational background of formation of sustainable lifestyle [PDF]

, 2013
In the XXI century mankind has approached the global transformation of society, which resulted in creation of a qualitatively new socioeconomic system, which is the knowledge society and the informational society, the foundation of which is the "economy ...
Jubran, J., Syukhina, A.G.
core  

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

Advanced Science, EarlyView.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu, Tianyang Wu, Jiayi Wang, Xinxing Du, Xinrui Wu, Yanhao Dong, Zehong Peng, Penghui Liao, Zirui Guo, Zheyu Liu, Kenneth J Pienta, Yinjie Zhu, Jiahua Pan, Liang Dong, Wei Xue   +14 more
wiley   +1 more source

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

Advanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang, Ying Hu, Yang Teng, Jiwei Qi, Yangzhen Ciren, Lin Zhang, Qiao Du, Wencai Xu, Liang Zhou, Zhenxin Fan, Jinchuan Xing, Ming Li, Jing Li   +12 more
wiley   +1 more source

EDUCATION FOR SUSTAINABLE DEVELOPMENT TODAY: A PROBLEM AREA FOR OVERCOMING DIFFICULTIES OF PEDAGOGICAL ADAPTATION (ON THE EXAMPLE OF A HIGHER SCHOOL)

Юг России: экология, развитие, 2018
Aim. The aim of this study is to structure the problem areas of pedagogical adaptation of the content of the concept of sustainable development into the practice of Russian higher education. Methods.
Yulia M. Grishaeva, Irina V. Wagner, Zinaida N. Tkacheva, Alexander M. Lugovskoy, Platon N. Moro   +4 more
doaj   +1 more source

Sense of Place in the Anthropocene: A students-teaching-students course [PDF]

, 2019
Contemporary environmental education is tasked with the acknowledgement of the Anthropocene - an informal but ubiquitous term for the current geological epoch which arose from anthropogenic changes to the Earth system - and its accompanying socio ...
Gaspero-Beckstrom, Giannina Sol, Mighell, Ella   +1 more
core   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Creativity and aesthetic applied to ecological education / Kūrybiškumas ir estetika ekologinėje edukacijoje

Creativity Studies, 2015
The present research attempts to reveal how ecological (environmental) education could be conveyed through aesthetic, visual art and various creative projects.
Agnieška Juzefovič
doaj   +1 more source

Экологическое образование и воспитание обучающихся [PDF]

, 2017
В данной статье рассмотрены задачи, принципы и модули экологического образования обучающихся, которые способствуют формированию экологического сознания и экологической культуры.This article describes the objectives, principles and modules for ...
Васильева, А. О., Ганюхина, О. Ю.   +1 more
core  

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source