Results 41 to 50 of about 443,658 (294)

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

From war memory to planetary consciousness: ecological postmemory and reconstructive metamodernism in Richard Flanagan’s Question 7

The Grove
This article examines Richard Flanagan’s Question 7 (2023) as a transformative work of postmemorial literature that fuses personal, historical, and ecological trauma within a metamodern framework.
Christina Angela Howes
doaj   +1 more source

Ethical considerations of urban ecological design and planning experiments

Plants, People, Planet, 2021
Societal Impact Statement It is increasingly common for plant scientists and urban planning and design professionals to collaborate on interdisciplinary teams that integrate scientific experiments into public and social urban spaces. However, neither the
Diane E. Pataki, Carlos G. Santana, Sarah J. Hinners, Alexander J. Felson, Jesse Engebretson   +4 more
doaj   +1 more source

Antecedents and outcomes of consumer environmentally friendly attitudes and behaviour [PDF]

, 2010
With the intensification of problems relating to the environment, a growing number of consumers are becoming more ecologically conscious in their preferences and purchases of goods.
Aitken L., Bentler P.M., Byrne B.M., Constantinos N. Leonidou, Dunlap R.E., Eigner S., Ellen P.S., Festinger L., Flatters P., García-Rosell J.-C., Hair J.F., Hofstede G., Hofstede G., Jones A., Kim Y., Kline R.B., Leonidas C. Leonidou, Levin G., Light H., Mayer F.S., McCarty J., Melillo W., Newell S.J., Nigbur D., Nisbet E.K., Nunnally J.C., O'Neill J., Olga Kvasova, Olli E., Paim L., Paladino A., Pickett G.M., Porritt J., Schuhwerk M.E., Shabecoff P., Sinha J.B.P., Sohr S., Solomon M., Triandis H.C.   +38 more
core   +3 more sources

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

Advanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır, Yuan Fang, Consuelo Contreras, Andrew K. Schulz, Florian Hartmann   +4 more
wiley   +1 more source

Genetic engineering for the environment: Ethical implications of the biotechnology revolution [PDF]

, 1995
This is a PDF version of an article published in Heythrop Journal© 1995. The definitive version is available at www.blackwell-synergy.com.This article discusses the environmental consequences of genetic engineering for agricultural purposes within a ...
Deane-Drummond, Celia
core   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Local-global policy in the context of an environmental crisis: proposition of a systemic analyse of environmental management. [PDF]

, 2010
Combining local and global policy on a cross bordered territory demands the building of a procedure. This is even more required in the case of environmental issues involving various actors who have to accept a common system of reference which guides the ...
Gartiser, Nathalie, Ohresser, Céline, Piquette, Élodie   +2 more
core  

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

Advanced Science, EarlyView.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu, Tianyang Wu, Jiayi Wang, Xinxing Du, Xinrui Wu, Yanhao Dong, Zehong Peng, Penghui Liao, Zirui Guo, Zheyu Liu, Kenneth J Pienta, Yinjie Zhu, Jiahua Pan, Liang Dong, Wei Xue   +14 more
wiley   +1 more source

>Starke< oder >schwache< Nachhaltigkeit?: Theologisch-ethische Überlegungen zur ökologischen Grundkomponente des Sustainability-Leitbilds [PDF]

, 2017
Worldwide implementation of the centrat concept sustainable development has given rise to very different interpretations, some extending to central issues within the field of ecological ethics.
Münk, Hans J.
core