Results 41 to 50 of about 1,694,341 (285)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Are current ecological restoration practices capturing natural levels of genetic diversity? A New Zealand case study using AFLP and ISSR data from mahoe (Melicytus ramiflorus) [PDF]

open access: yes, 2015
Sourcing plant species of local provenance (eco-sourcing) has become standard practice in plant community restoration projects. Along with established ecological restoration practices, knowledge of genetic variation in existing and restored forest ...
Goshorn, Mary   +5 more
core  

"Ecological Genetics" in Genetic Education System of Sankt-Petersburg State University

open access: yes, 2007
The introductory paper to this issue of the Journal presents the position and the meaning of ecological genetics in general system of basic genetic education.
Sergey G Inge-Vechtomov
core   +1 more source

Evolutionary genetics of naturally and sexually selected traits in cichlid fishes [PDF]

open access: yes, 2014
In my PhD thesis I use cichlid fishes as model system to study the evolutionary genetics of naturally and sexually selected traits. Several traits of cichlid fishes such as; the pharyngeal jaw apparatus, haplochromine maternal mouthbrooding, egg-spots ...
Diepeveen, Eveline Tamara
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Functional mutations in the thyroid-stimulating hormone receptor in natural stickleback populations at sites identical to human disease-causing mutations

open access: yesBMC Ecology and Evolution
Background Thyroid hormones regulate multiple physiological functions, including metabolism, reproduction, and metamorphosis. Although there are variations in thyroid hormone signaling between populations and species, the causative mutations underlying ...
Jun Kitano   +6 more
doaj   +1 more source

Ecological Genetics for the 21st Century [PDF]

open access: yes, 1995
In the spring of 1991, the University of North Carolina hosted a series of seminars on the topic of ecological genetics. Five distinguished researchers, Montgomery Slatkin, Sara Via, Michael Lynch, Janis Antonovics, and Joseph Travis, were each invited ...
Bowen, Bonnie S
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Genome-wide analysis of histone modifications can contribute to the identification of candidate cis-regulatory regions in the threespine stickleback fish

open access: yesBMC Genomics
Background Cis-regulatory mutations often underlie phenotypic evolution. However, because identifying the locations of promoters and enhancers in non-coding regions is challenging, we have fewer examples of identified causative cis-regulatory mutations ...
Genta Okude   +4 more
doaj   +1 more source

THE ROLE OF GENETICS IN MODERN MEDICINE

open access: yesБайкальский медицинский журнал, 2022
The lecture examines the role of modern genetics and its significance for medicine. The goals of genetics and its structure are determined. It is shown that modern medical genetics is divided into general genetics, clinical genetics and laboratory ...
Elena Anatolyevna Tkachuk   +1 more
doaj   +1 more source

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