Results 151 to 160 of about 2,521,556 (294)

Single‐Vesicle Functional Nanophenotyping Reveals Heterogeneous PD‐L1 Accessibility in Triple‐Negative Breast Cancer

Small Methods, EarlyView.
Graphical Abstract. High‐speed atomic force microscopy enables real‐time, label‐free visualization of antibody interactions with individual extracellular vesicles. By quantifying binding frequency and dwell time, this approach reveals functional PD‐L1 accessibility that cannot be inferred from protein abundance alone, uncovering nanoscale heterogeneity
Reon Imakawa, Keesiang Lim, Takeshi Yoshida, Tomoyoshi Yamano, Tsunaki Hongu, Uryo Onishi, Masaharu Hazawa, Toshio Ando, Noriko Gotoh, Rikinari Hanayama, Richard W. Wong   +10 more
wiley   +1 more source

Toward an Intermediate Structural Representation of Organization in Complex Systems

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Organization is widely recognized as a fundamental concept in complex systems science, yet it rarely appears as an explicit object of scientific representation. Existing approaches successfully represent components, interactions, mechanisms, dynamical states, networks, or functions, but organizational properties are generally inferred from ...
Paméla Magotte
wiley   +1 more source

Comment on "Haemophilus abundance is associated with response to sublingual immunotherapy in children with allergic rhinitis". [PDF]

Pediatr Allergy Immunol
Kaplan F.
europepmc   +1 more source

Insights into Reproductive Immunology and Placental Pathology, 2nd Edition

This Special Issue, the second one dedicated to reproductive immunology and placental pathology, is a response to the need to summarize the latest trends in research topics in this field [...
Dariusz Szukiewicz
core   +1 more source

Agricultural Fungicide Mancozeb in Leaf Litter Enhances Survival and Growth of Aedes aegypti (Diptera: Culicidae)

Environmental Toxicology, EarlyView.
ABSTRACT Mancozeb is one of the most widely used agricultural fungicides, exhibiting strong efficacy against a broad spectrum of phytopathogenic fungi. However, its widespread application comes at the cost of environmental contamination. Here, we show the effects of Inga vera leaf litter contamination with Mancozeb on life‐history traits of Aedes ...
Heloise Restello Remus, Gilberto Dinis Cozzer, João Tauchert, Raquel de Brito, Cássia Alves Lima‐Rezende, Jacir Dal Magro, Natalia Bastiani da Luz, Daniel Albeny‐Simões, Renan de Souza Rezende   +8 more
wiley   +1 more source

Editorial: Commending 20 years since the formal discovery of immune priming: the innate immune memory

Frontiers in Immunology
Jorge Contreras-Garduño, Joachim Kurtz
doaj   +1 more source

Navigating the Panzootic Era of HPAI H5N1: Bridging Surveillance and Countermeasure Deficits. [PDF]

Viruses
Perez DR.
europepmc   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

Environmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão, Igor Romeiro dos Santos, Jerônimo Raimundo de Oliveira Neto, Flávio Olimpio Sanches Neto, Felipe Cirqueira Dias, Jéssyca Moreira Morais, Lorranny Pereira de Assis Valadares, Naiara Raica Lopes de Oliveira, Mirelle Garcia Silva Bailão, Luiz Carlos da Cunha, Valter Henrique Carvalho‐Silva, Thiago Lopes Rocha, Elisa Flávia Luiz Cardoso Bailão   +12 more
wiley   +1 more source

Many hosts, many solutions: How reservoirs shape Borrelia protein diversity. [PDF]

PLoS Pathog
Ciglbauerová S, Strnad M, Rego ROM.
europepmc   +1 more source

The 5T Paradox of Triclosan: From Toiletries to Toxic Trash, a Growing Threat to Humanity

Environmental Toxicology, EarlyView.
ABSTRACT Triclosan (TCS) persists as a contaminant of concern in the Anthropocene, despite regulatory actions. Environmental dissemination continues through wastewater effluents, biosolid application, and improper disposal practices. This narrative review synthesizes current evidence regarding triclosan's environmental fate, transformation pathways ...
Temitope Aribigbola, Mauro Ricardo Souza da Luz, Sunday Amos Onikanni, Marjorie Dardis Murucci, Oluwatosin Stella Olayinka, Rodrigo Soares Fortunato, Rômulo Sperduto Dezonne, Omolola Esther Amos, Sara Gemini Piperni, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source