Results 41 to 50 of about 119,816 (255)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Investigating the spatio-temporal interactive relationship between land use structure and ecosystem services in urbanizing China

Ecological Indicators
The negative impacts of urbanization-triggered land use changes on ecosystem services have attracted worldwide attention. However, the interactive relationships between land use structure and ecosystem services remain unclear, which is not conducive to ...
Shaofeng Yuan, Zhiheng Mei, Congmou Zhu, Ruifen Cao, Sinan Li, Lixia Yang, Yue Su, Wuyan Li   +7 more
doaj   +1 more source

Necessary or oversimplification? On the strengths and limitations of current assessments to integrate social dimensions in planetary boundaries

Ecological Indicators, 2021
With the Earth system being about to leave Holocene conditions and thus the known safe operating space for humanity, frameworks such as the Planetary Boundaries (PBs) and the Sustainable Development Goals (SDGs) provide quantitative metrics to guide ...
Lukas Drees, Robert Luetkemeier, Heide Kerber   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Quantifying spatial ignorance in the effort to collect terrestrial fauna in Namibia, Africa

Ecological Indicators
Effective conservation efforts and predictions of future impacts on biodiversity depend heavily on publicly available information about species distributions.
Thainá Lessa, Fernanda Alves-Martins, Javier Martinez-Arribas, Ricardo A. Correia, John Mendelsohn, Ezequiel Chimbioputo Fabiano, Simon T. Angombe, Ana C.M. Malhado, Richard J. Ladle   +8 more
doaj   +1 more source

Construction of a human-wildlife spatial interaction index in the Three-River Source Region, China

Ecological Indicators, 2021
In the context of today’s rapid economic development and increasingly strict ecological protection, interactions between humans and wildlife will intensify. Therefore, we need to identify the spatial distribution of such interactions and to take measures
Bingran Ma, Yuxi Xie, Tongzuo Zhang, Weihua Zeng, Yinglan Xue   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

What are the key and catalytic external factors affecting the vitality of urban blue-green space? a case study of Nanjing Main Districts, China

Ecological Indicators
In recent years, urban blue-green space has received increasing attention as an important carrier of urban spatial vitality. It has become increasingly clear that urban blue-green spaces both cities and citizens, though these concepts of spatial vitality
Zhifan Ding, Hui Wang
doaj   +1 more source

Ecosystem-Based Quality Index in a harbor bay: Assessing the status of a heterogeneous system in a functional framework at a local scale

Ecological Indicators, 2021
The assessment of natural ecosystem status is a fundamental premise to enable environmental management at local scales to maintain ecosystem functioning, services and resilience.
Filippo Ferrario, Ladd E. Johnson, Christopher W. McKindsey, Philippe Archambault   +3 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source