Results 41 to 50 of about 283,808 (265)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Dynamic monitoring and analysis of factors influencing ecological quality in rapidly urbanizing areas based on the Google Earth Engine

open access: yesGeocarto International, 2023
Rapid urbanization poses significant challenges to ecological preservation in karst ecologically fragile regions. Systematically monitor and evaluate of its urban ecological pattern change and driving factors are the basis for achieving regional ...
Fuxianmei Zhang   +6 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Dynamics of Land Use/Land Cover Considering Ecosystem Services for a Dense-Population Watershed Based on a Hybrid Dual-Subject Agent and Cellular Automaton Modeling Approach

open access: yesEngineering
Land use/land cover represents the interactive and comprehensive influences between human activities and natural conditions, leading to potential conflicts among natural and human-related issues as well as among stakeholders.
Yutong Li   +5 more
doaj   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Contrasting effects of iron minerals on soil organic carbon stability in mangrove wetlands with different salinities

open access: yesEcological Processes
Background Iron (Fe) oxides are vital for the stability of soil organic carbon (SOC) in wetlands, yet their impact on SOC stability in mangrove wetlands with varying salinity levels remains unclear.
Haixiao Zhao   +5 more
doaj   +1 more source

Is Young's Modulus a Critical Coating Property Determining Fouling‐Release Performance of Marine Coatings?

open access: yesAdvanced Engineering Materials, EarlyView.
The release of foulers from protective marine coatings is determined by several interrelated material properties, including the strength of Young's modulus, the flexibility of chain segments, the surface free energy, and the magnitude of hydrodynamic stress.
Johann C. Schaal   +2 more
wiley   +1 more source

Landscape Preferences, Ecological Quality, and Biodiversity Protection [PDF]

open access: yesEnvironment and Behavior, 2002
The loss of biological diversity is a major environmental problem occurring on a global scale. Human-environment researchers have an important role in shaping policy and programs at a local, national, and international level. This article explores human preference for landscapes relative to ecological quality and assesses the relationship between ...
Cary, John, Williams, Kathryn
openaire   +1 more source

Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability

open access: yesAdvanced Engineering Materials, EarlyView.
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner   +3 more
wiley   +1 more source

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