Results 101 to 110 of about 330,792 (296)

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang   +11 more
wiley   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Island time and the interplay between ecology and evolution in species diversification. [PDF]

open access: yes, 2015
Research on the dynamics of biodiversity has progressed tremendously over recent years, although in two separate directions - ecological, to determine change over space at a given time, and evolutionary, to understand change over time.
Gillespie, Rosemary G
core   +1 more source

Sugar Metabolism and Transport in Response to Drought–Rehydration in Poa pratensis

open access: yesAgronomy
Poa pratensis is one of the world’s most widely planted cold-season turfgrasses, with good quality but poor drought resistance. When plants suffer from stress, the metabolism of soluble sugar takes place, which is a dynamic process involving both ...
Jiangdi Yu   +4 more
doaj   +1 more source

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen   +6 more
wiley   +1 more source

Are current ecological restoration practices capturing natural levels of genetic diversity? A New Zealand case study using AFLP and ISSR data from mahoe (Melicytus ramiflorus) [PDF]

open access: yes, 2015
Sourcing plant species of local provenance (eco-sourcing) has become standard practice in plant community restoration projects. Along with established ecological restoration practices, knowledge of genetic variation in existing and restored forest ...
Clarke, Andrew C.   +4 more
core   +2 more sources

Integrating trait-based empirical and modeling research to improve ecological restoration [PDF]

open access: yes, 2018
A global ecological restoration agenda has led to ambitious programs in environmental policy to mitigate declines in biodiversity and ecosystem services.
Fiedler, Sebastian   +2 more
core   +1 more source

Annual Variation of Secondary Productivity of Macroben-Thos Based on Brey Estimation Model

open access: yesHaiyang Kaifa yu guanli
In this study, we took the East Fujian ecological monitoring area as an example, using Brey's empirical formula to analyzed the characteristics of Macrobenthos Community Structure and the interannual variation of secondary productivity based on the ...
CHENG Hong   +7 more
doaj  

Principles for Rigorous Design and Application of Synthetic Microbial Communities

open access: yesAdvanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang   +21 more
wiley   +1 more source

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