Results 91 to 100 of about 7,075,928 (250)

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang   +9 more
wiley   +1 more source

Evaluation of Water Ecological Security in Poyang Lake and Its Key Influencing Factors [PDF]

open access: yes长江科学院院报
[Objectives] Water ecological security assessment serves as a crucial tool for evaluating the safety and sustainability of aquatic ecosystems. However, few studies have combined dimensionality reduction techniques with ensemble machine learning methods ...
ZHANG Yi-yi, SHEN Yu-ying, XU Li-gang, CHENG Jun-xiang, WU Ya-kun, LUAN Hua-long, QU Geng
doaj   +1 more source

Wageningen views on food security [PDF]

open access: yes, 2002
Report that integrates the proceedings of a number of multidisciplinay expert workshops on food security at Wageningen ...
Koning, N.B.J.   +2 more
core  

Ammonification Process Is Limited by Transformation of Medium Molecular Weight Nitrogenous Organics but Not Hydrolysis of Proteins

open access: yesAdvanced Science, EarlyView.
A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Jing Li   +4 more
wiley   +1 more source

Spatiotemporal Evolution and Obstacle Factor Analysis of Land Ecological Security in the Surrounding Areas of Beijing, China

open access: yesLand
Land ecological security is essential for sustainable land resource use and socioeconomic development. This study presents an evaluation index system combining single-indicator quantification, multi-indicator integration, and multi-criteria comprehensive
Yutong Wang, Jianyu Yang
doaj   +1 more source

Nevada National Security Site 2010 Waste Management Monitoring Report Area 3 and Area 5 Radioactive Waste Management Sites [PDF]

open access: yes, 2011
Environmental monitoring data were collected at and around the Area 3 and Area 5 Radioactive Waste Management Sites (RWMSs) at the Nevada National Security Site (NNSS).
National Security Technologies, LLC
core   +1 more source

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

open access: yesAdvanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng   +10 more
wiley   +1 more source

National Security Commission on Artificial Intelligence: Interim Report, November 2019 [PDF]

open access: yes, 2019
Report presenting the National Security Commission on Artificial Intelligence's initial (NSCAI)'s preliminary assessment of artificial intelligence (AI).
National Security Commission on Artificial Intelligence (U.S.)
core  

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

open access: yesAdvanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang   +20 more
wiley   +1 more source

Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High‐Fat Diet‐Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu   +10 more
wiley   +1 more source

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