Results 81 to 90 of about 6,783 (211)
Advanced Science, EarlyView.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +1 more source
Ecology and Evolutionary Biology as Frameworks to Study Wine Fermentations
Microbial BiotechnologyABSTRACT Winemaking has leveraged microbiology to enhance wine quality, typically by engineering and inoculating individual yeast strains with desirable traits. However, yeast strains do not grow alone during wine fermentation, rather they are embedded in diverse and evolving microbial communities exhibiting complex ecological ...
Ignacio Belda +4 more
openaire +5 more sources
Advanced Science, EarlyView.A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
wiley +1 more source
A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics
Advanced Science, EarlyView.A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma +22 more
wiley +1 more source
Advanced Science, EarlyView.An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang +15 more
wiley +1 more source
Advanced Science, EarlyView.Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang +7 more
wiley +1 more source
Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice
Nature CommunicationsLaboratory mice (Mus musculus domesticus) harbor gut bacterial strains that are distinct from those of wild mice but whose evolutionary histories are unclear.
Daniel D. Sprockett +4 more
doaj +1 more source
Advanced Science, EarlyView.A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma +11 more
wiley +1 more source
Scientific ReportsThe temperature sensitivity of soil microbial respiration, commonly quantified using the Q10 coefficient, is a key parameter in carbon cycle models. Uncovering how environmental factors affect in situ Q10 values can therefore provide critical insight ...
Melanie T. Hacopian +6 more
doaj +1 more source
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
Advanced Science, EarlyView.While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source