Results 181 to 190 of about 638,432 (288)
Glycative Stress Disrupts the Mitochondrial‐Lysosome Axis and Promotes Geroconversion in Aging Cardiomyocytes
Aging Cell, Volume 25, Issue 3, March 2026.Cardiac aging promotes mitochondrial AGE accumulation driven by defective glycative stress detoxification. AGE‐modified mitochondria disrupt lysosomal proteolysis, impairing mitophagy and promoting lipofuscin buildup. This mechanism sustains chronic unresolved mitochondrial damage, driving proinflammatory senescence in cardiomyocytes and defining a ...Diana Bou‐Teen, Simonas Valiuska, Elisabet Miro‐Casas, Chiara Rubeo, Elena Bonzon‐Kulichenko, Zuzana Nichtova, Celia Fernandez‐Sanz, Javier Inserte, Antonio Rodriguez‐Sinovas, Begoña Benito, Eduard Ródenas‐Alesina, Jesús Vázquez, Ignacio Ferreira‐González, Marisol Ruiz‐Meana +13 morewiley +1 more sourcePrognostic value of fetal growth and prenatal functional echocardiography in tetralogy of FALLOT
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 3, Page 479-491, March 2026.First demonstration that fetal growth and pulmonary peak velocity at third trimester are independent predictors of postnatal outcome in Tetralogy of Fallot. This may enhance the accuracy of prenatal counseling and facilitate more individualized planning for delivery and neonatal care. Abstract Introduction
Tetralogy of Fallot (ToF) shows variability in Laura Nogué, Mar Bennasar, Laura Guirado, Felix Zölner, Justus Reitz, Roland Axt‐Fliedner, María C. Escobar‐Díaz, Josep Maria Martínez, Eduard Gratacós, Fàtima Crispi, Olga Gómez, for the BCNatal and Gießen and Marburg University investigators, Míriam Pérez‐Cruz, Narcís Masoller, Franziska Holland, Mireia Caballero, Marta Guilleumes, Sergi Cesar +17 morewiley +1 more sourceThe OLGIMA system for gastric cancer risk assessment. A useful method based on the histological Sydney consensus
Histopathology, Volume 88, Issue 4, Page 911-921, March 2026.The new OLGIMA method for histological gastric cancer risk assessment is based on the severity of glandular atrophy and intestinal metaplasia, in both antrum and corpus, according to the Updated Sydney classification. The highest score of either atrophy or intestinal metaplasia from each location will be used for the final OLGIMA stage.Pedro Genaro Delgado Guillena, Miriam Cuatrecasas, Sheyla Montori, Nayra Felipez Varela, Joan Llach, Iva Archilla, Pablo Florez‐Diez, Eva Barreiro‐Alonso, Javier Tejedor‐Tejada, Raquel Vicente, M Teresa Soria, Alaín Huerta, Silvia Patricia Ortega, Henar Nuñez, Oliver Patrón, Carolina Mangas, Diana Zaffalon, Luis Hernández, Luis Enrique Yip, Gadea Hontoria, Gonzalo Hijos, Maria Jose Domper‐Arnal, Sara Zarraquiños, Alberto Herreros De Tejada, Alicia Córdoba, Anabella Cuestas, Glòria Fernández‐Esparrach, Leticia Moreira, Eduardo Albéniz, on behalf of EpiGASTRIC/EDGAR Consortium, Joan Llach, Sheyla Montori, Anabella Cuestas, Gloria Fernandez‐Esparrach, Nayra Felipez Varela, Fermín Estremera‐Arevalo, Marta Gómez Alonso, Juan José Vila Costas, Victoria Busto Bea, Juan Carrascosa Gil, Vanesa Jusué Irurita, Alicia Córdoba Iturriagagoitia, Concepción Llanos Chavarri, Irene Amat Villegas, Gregorio Aisa Rivera, Irene Fernández de los Reyes, Gina de Lima Piña, Miguel Ángel Resano, Adriana Yague Hernando, Cristina Caballero Martínez, Alfredo López Cousillas, Miriam Cuatrecasas, Pedro Genaro Delgado Guillena, Javier Tejedor, Elena Arruebo, Silvia Patricia Ortega, Henar Nuñez, Pilar Diez, Diana Zaffalon, Luis Hernández, Gadea Hontoria, Rosa Maria Saíz, Gonzalo Hijos, María Jose Domper, Sara Zarraquiños, Astrid Irene, Alberto Herreros, Diego de Frutos, Fatima Valentin, Jose Santiago, Virginia Piñol, Adelina García, Alicia Martín‐Lagos, Pablo Florez, Eva Barreiro, Adolfo Suarez, Raquel Vicente, M Teresa Soria, Cristina Polo, Carmen Yagüe, Alain Huerta, Oliver Patrón, David Tello, Carolina Mangas, Eva Serrano, Juan Martínez, Rodrigo Jover, Raquel Grajal, Luis Enrique Yip, Patricia Gonçalves, Jenifer Muñoz, Cristina Herrera‐Pariente, Laia Bonjoch, Sergi Castellví‐Bel, Dulce Momblan, Tamara Saurí, Irina Luzko, Elisa Cantú‐Germano, Angels Gines, Ignasi Elizalde, Francesc Balaguer, Angelez Perez‐Aisa, Jennifer Hinojosa, Coral Tejido, Laura Rivas, María Francisco, Manu Puga, Franco Baiocchi, Cristina Alejandra Sánchez, Alba Pereiros, Joaquin Cubiella, Alejandro Ledo, Ma Victoria Alvarez, Marta Garzón, Juan Manuel Martín, Salvador Sobrino, Ana García‐Rodríguez, Ines Gil, Alazne Aguirre, Ainara Maiz, Ines Ariño, María Dolores Pico, Beatriz de Riba, Goretti Hernández, Eduardo Albéniz, Leticia Moreira +125 morewiley +1 more sourceInterobserver variability of histopathological assessment in pT1 colorectal carcinoma
Histopathology, Volume 88, Issue 4, Page 868-880, March 2026.Interobserver variability among 20 gastrointestinal pathologists was evaluated on 80 pT1 colorectal carcinoma cases. A pilot phase was followed by a consensus meeting, then a larger concordance study was performed. High interobserver agreement was achieved after consensus for histological grade, lymphovascular invasion, tumour budding, poorly ...Karmele Saez de Gordoa, María Daca‐Alvarez, Maite Rodrigo‐Calvo, Ivan Archilla, Sandra Lopez‐Prades, Jose Javier Aguirre, Lorena Alarcón‐Molero, María Cámara Jurado, Adriana Canosa, Francisco Giner, Carmen González‐Lois, Mireya Jimeno, Ismael Jurado, Isidro Machado, Carolina Martínez‐Ciarpaglini, Eva Musulen, Dolores Naranjo, Natalia Papaleo, Cristina Peña, Òria Rosiñol, Rosario Sánchez‐Yuste, Greissy Tibisay Vázquez Benítez, María Pellisé, Miriam Cuatrecasas, on behalf of the EpiT1 Consortium +24 morewiley +1 more source