A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
The Predominant Role of Musical Valence Over Arousal in Pain Modulation: A Psychophysiological Study. [PDF]
Abrahan VD, Alba G, Justel N, Muñoz MA.
europepmc +1 more source
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios +18 more
wiley +1 more source
Patient Stratification for Serum LDH Levels Reveals Distinct CLA<sup>+</sup> T-Cell Cytokine Secretion in Response to HDM, Clinical Features and Allergic Comorbidities. [PDF]
García-Jiménez I +12 more
europepmc +1 more source
Terrain Synthesis and Authoring based on Iso‐Contours
Abstract Digital terrains are central to realistic landscape depiction, yet authoring tools must balance perceptual realism with intuitive artistic control. We propose a compact vector‐based representation that models terrain as nested iso‐contours, inspired by geomorphology and cartography.
B. Huftier +5 more
wiley +1 more source
Correction: Some new evidence using fractional integration about trends, breaks and persistence in polar amplification. [PDF]
Caporale GM +2 more
europepmc +1 more source
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.
Jaime Bernaola +14 more
wiley +1 more source
Tracking the impact of bottom trawling on benthic habitat status
Abstract Bottom trawling is the most widespread physical disturbance to marine benthic habitats, yet broadscale assessments of its impact remain limited. We developed a quantitative framework to evaluate trawling effects on benthic habitats at broad spatial scales based on the sentinels of seabed (SoS) indicator.
Maider Plaza‐Morlote +10 more
wiley +1 more source
Efficacy of NAMPT Inhibitors in Pancreatic Cancer After Stratification by MAP17 (PDZK1IP1) Levels. [PDF]
Verdugo-Sivianes EM +4 more
europepmc +1 more source
New insights into the determinants of willingness to pay for supporting professional sport teams
Abstract This paper examines the determinants of individuals' willingness to pay (WTP) to prevent the relegation of a professional football team. Drawing on an analytical framework provided by social capital and social identity theories, we hypothesize that social trust and civic pride are key predictors of WTP.
Jaume García +3 more
wiley +1 more source

