Results 261 to 270 of about 1,052,870 (313)

Microbiome‐Based Modeling of CAR‐T Therapy Response in Lymphoma: Insights From Shotgun Metagenomics Sequencing

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell‐driven cancer immunotherapies. However, clinical studies supporting microbiota‐based interventions in chimeric antigen receptor T‐cell (CAR‐T) therapy remain scarce.
Rafael Hernani   +22 more
wiley   +1 more source

Extracellular vesicle proteomics identifies novel blood biomarkers for the early diagnosis of status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina   +11 more
wiley   +1 more source

Civic participation among young people in Chile: an association analysis in times of COVID-19. [PDF]

open access: yesRev Esc Enferm USP
Saldías-Fernández MA   +4 more
europepmc   +1 more source

The Impact of Risk Exposure and Environmental Conditions on European Banking Efficiency

open access: yesEuropean Financial Management, EarlyView.
ABSTRACT This study investigates the determinants of bank cost efficiency in Europe by applying a dynamic Bayesian stochastic frontier approach. We distinguish between two conceptually and empirically separate components of efficiency: (1) an intrinsic component, driven by internal bank features such as size and risk exposure, and (2) an extrThis study
Pilar Gargallo   +2 more
wiley   +1 more source

Elucidating the Molecular Basis in a Cohort of Patients With Combined Bleeding Tendencies and Joint Hypermobility Manifestations

open access: yesHaemophilia, EarlyView.
ABSTRACT Background In patients with unexplained bleeding and normal haemostatic parameters, heritable disorders of connective tissue (HDCT) may be an underlying cause due to vascular fragility, as observed in Ehlers–Danlos syndrome (EDS) or Marfan syndrome (MS). This study aims to investigate the molecular profile of patients with joint hypermobility (
Perla Bandini   +11 more
wiley   +1 more source

The OLGIMA system for gastric cancer risk assessment. A useful method based on the histological Sydney consensus

open access: yesHistopathology, EarlyView.
The new OLGIMA method for histological gastric cancer risk assessment is based on the severity of glandular atrophy and intestinal metaplasia, in both antrum and corpus, according to the Updated Sydney classification. The highest score of either atrophy or intestinal metaplasia from each location will be used for the final OLGIMA stage.
Pedro Genaro Delgado Guillena   +125 more
wiley   +1 more source

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