Results 91 to 100 of about 4,361 (205)

Impact of Prior Biologic Mechanism of Action on Anti‐TNF Effectiveness in Inflammatory Bowel Disease: An ENEIDA Registry Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this nationwide ENEIDA registry study, anti‐TNF therapy after prior exposure to a different biologic mechanism of action showed reduced treatment durability in inflammatory bowel disease, with a particularly marked impact in ulcerative colitis, where short‐ and long‐term clinical effectiveness was also lower. ABSTRACT Background The expanding use of
Carmen Yagüe Caballero   +85 more
wiley   +1 more source

Decellularised Corneal Stromal Lamina With or Without Autologous Adipose‐Derived Adult Stem Cells for Advanced Keratoconus: 1‐Year Results of a Phase I/IIa Clinical Trial

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang   +7 more
wiley   +1 more source

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum

open access: yesClinical Genetics, EarlyView.
Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz   +23 more
wiley   +1 more source

TreeON: Reconstructing 3D Tree Point Clouds from Orthophotos and Heightmaps

open access: yesComputer Graphics Forum, EarlyView.
Abstract We present TreeON, a novel neural‐based framework for reconstructing detailed 3D tree point clouds from sparse top‐down geodata, using only a single orthophoto and its corresponding Digital Surface Model (DSM). Our method introduces a new training supervision strategy that combines both geometric supervision and a differentiable shadow and ...
Angeliki Grammatikaki   +4 more
wiley   +1 more source

Terrain Synthesis and Authoring based on Iso‐Contours

open access: yesComputer Graphics Forum, EarlyView.
Abstract Digital terrains are central to realistic landscape depiction, yet authoring tools must balance perceptual realism with intuitive artistic control. We propose a compact vector‐based representation that models terrain as nested iso‐contours, inspired by geomorphology and cartography.
B. Huftier   +5 more
wiley   +1 more source

Gerenciamento de medicamentos em desuso devolvidos por pacientes ambulatoriais de um hospital universitário

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2014
O presente trabalho teve como objetivo avaliar o perfil das devoluções de medicamentos não utilizados à farmácia do Componente Especializado da Assistência Farmacêutica do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, da Universidade ...
Lilian Pereira Primo   +5 more
doaj  

Step2Motion: Locomotion Reconstruction from Pressure Sensing Insoles

open access: yesComputer Graphics Forum, EarlyView.
Abstract Human motion is fundamentally driven by continuous physical interaction with the environment. Whether walking, running, or simply standing, the forces exchanged between our feet and the ground provide crucial insights for understanding and reconstructing human movement. Recent advances in wearable insole devices offer a compelling solution for
J. L. Ponton   +5 more
wiley   +1 more source

Analysis of the relationship between firm innovation and corporate social responsibility: A systematic literature review

open access: yesEuropean Management Review, EarlyView.
Abstract Firm innovation and corporate social responsibility (CSR) are key strategic considerations that shape a firm's competitiveness and sustainability. However, studies exploring the relationship between the two are heterogeneous and sometimes obtain contradictory results, making it difficult to draw clear conclusions.
Daniel Alonso‐Martínez   +2 more
wiley   +1 more source

Changes in the Turnover Ratio and Liquidity in International Equity Markets

open access: yesEuropean Financial Management, EarlyView.
ABSTRACT We examine global trading activity over 15 years and compare trends across countries. We find that European volume has grown, but less than in other countries, while turnover ratios have declined. However, the decline is exaggerated in standard volume data, which focuses on primary market trading, and becomes comparable after adjusting North ...
Jose S. Penalva, Mikel Tapia
wiley   +1 more source

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