Results 151 to 160 of about 2,905 (260)
Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum
Clinical Genetics, EarlyView.Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz +23 more
wiley +1 more source
Impact of Ser81 phosphorylation on alanine: glyoxylate aminotransferase associated with Primary hyperoxaluria type I. [PDF]
Mol BiomedMilosevic S +4 more
europepmc +1 more source
LOGISTICA REVERSA NA ECONOMIA CIRCULAR
A crescente preocupação com a sustentabilidade e a escassez de recursos naturais têm impulsionado a adoção de práticas de logística reversa e economia circular por empresas de diversos setores. A logística reversa permite a recuperação de produtos e materiais pós-consumo, reduzindo o desperdício e promovendo a reutilização e reciclagem. Este artigo tem
openaire +1 more source
Terrain Synthesis and Authoring based on Iso‐Contours
Computer Graphics Forum, EarlyView.Abstract Digital terrains are central to realistic landscape depiction, yet authoring tools must balance perceptual realism with intuitive artistic control. We propose a compact vector‐based representation that models terrain as nested iso‐contours, inspired by geomorphology and cartography.
B. Huftier +5 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio +38 more
wiley +1 more source
European Management Review, EarlyView.Abstract Firm innovation and corporate social responsibility (CSR) are key strategic considerations that shape a firm's competitiveness and sustainability. However, studies exploring the relationship between the two are heterogeneous and sometimes obtain contradictory results, making it difficult to draw clear conclusions.
Daniel Alonso‐Martínez +2 more
wiley +1 more source
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.
Jaime Bernaola +14 more
wiley +1 more source
The FEBS Journal, EarlyView.Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero +8 more
wiley +1 more source
Insect Conservation and Diversity, EarlyView.Here, we used a unique 37‐year (1969–2006) freshwater macroinvertebrate time‐series, collected over seven sites in central Germany, to study biodiversity patterns and species accumulation over time. Accumulation curves of Diptera diversity have not reached a plateau in 37 years of sampling.
Nathan Jay Baker +10 more
wiley +1 more source
Insect Conservation and Diversity, EarlyView.Constant visitation rates across the flowering season masked major shifts in plant and flower visitor interaction structure, specialization, species roles and trait‐driven patterns shaping interaction intensity. Plants and flower visitors changed ecological roles over time, with native flower visitors playing key roles in maintaining network cohesion ...
Alba Costa +3 more
wiley +1 more source