Results 231 to 240 of about 153,853 (263)

MGL‐Based Drug Conjugate: A Novel Glycan‐Targeting Strategy for Potential Precision Cancer Therapy

ChemistryEurope, Volume 4, Issue 5, May 2026.
An engineered macrophage galactose‐type lectin (MGL)‐based conjugate (mMGL‐vcMMAE), incorporating an exposed cysteine for site‐specific drug linkage, preserves stability, binding profile, and affinity of the native MGL carbohydrate recognition domain. It also selectively targets Tn/STn‐expressing cancer cells and shows recognition of colorectal cancer ...
Carlos D. L. Lima, Rafaela Abrantes, Victor Lorrain, Joana Gomes, Reyes Núñez‐Franco, João P. M. António, Catarina Gomes, Ana Gimeno, Benedita A. Pinheiro, Angelina S. Palma, Jesús Jiménez‐Barbero, Pedro M. P. Gois, Gonzalo Jiménez‐Osés, Sandra J. van Vliet, Celso A. Reis, Filipa Marcelo   +15 more
wiley   +1 more source

Unravelling the Significance of Phosphoenolpyruvate Carboxylase in Phosphate Starvation Responses. [PDF]

Plant Cell Environ
Pérez-López J, de la Osa C, Gandullo J, Gigli-Bisceglia N, Coleto I, Feria AB, Echevarría C, Testerink C, Marino D, García-Mauriño S, Monreal JA.   +10 more
europepmc   +1 more source

Hair Cortisol Concentrations in Children: A Longitudinal Analysis Across Childhood

Developmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Hair cortisol concentration (HCC) reflects long‐term cortisol exposure and is commonly used as a biomarker of hypothalamic–pituitary–adrenal axis activity. Although increasingly applied in pediatric populations, developmental changes in HCC and potential sex differences remain unclear.
Miguel Ángel Baos‐González, Javier De Echarri‐Lorente, María Ángeles García‐León, Raquel González‐Pérez, María Isabel Peralta‐Ramírez   +4 more
wiley   +1 more source

Comparative assessment of two circularity indicators for the case of reusable versus single-use secondary packages for fresh foods in Spain. [PDF]

Heliyon
Sazdovski I, Batlle-Bayer L, Bala A, Margallo M, Azarkamand S, Aldaco R, Fullana-I-Palmer P.   +6 more
europepmc   +1 more source

Asymmetric Information With Multiple Risks: The Case of the Chilean Private Health Insurance Market

Health Economics, Volume 35, Issue 5, Page 712-729, May 2026.
ABSTRACT We extend the Rothshild and Stiglitz (1976) model to two sources of risk –inpatient and outpatient risk– to better proxy real‐world health insurance markets. We uncover an interesting theoretical possibility: Take individuals A and B, who are low risks in, say, the inpatient dimension but A is riskier in the outpatient dimension.
Dolores de la Mata, Matilde P. Machado, Pau Olivella, Nieves Valdés   +3 more
wiley   +1 more source

Shape-Matching and Halogen Bonding in Chiral Pyrazine-Allene Hosts: Confining an Unstable Guest Conformation. [PDF]

Org Lett
Rubio-Pisabarro V, Álvarez-García J, Cid MM.   +2 more
europepmc   +1 more source

Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions. [PDF]

Sci Rep
Vega C, Medina N, Quintana-Quintana L, Leon R, Fabelo H, Rial J, Martín A, Callico GM.   +7 more
europepmc   +1 more source

Numerical and experimental study of the optimal specimen geometry for direct tension strength tests in high tensile strength fiber reinforced concrete. [PDF]

Sci Rep
Vicente MA, Mena-Alonso Á, González DC, Ruiz G, Cifuentes H, Leiva C, Yu R, Mínguez J.   +7 more
europepmc   +1 more source

Enzyme Benchmarking with Polyethylene Furanoate Soluble Scaffolds for Directed Evolution of PEFases. [PDF]

ACS Omega
Dolz M, Monterrey DT, Quartinello F, de Santos PG, Mateljak I, Pellis A, Guebitz G, Viña-González J, Alcalde M.   +8 more
europepmc   +1 more source

Significant Detection of Porcine Circovirus 3 and Porcine Circovirus 4 in Wild Boars from Mid-Western Spain Without Apparent Sanitary Consequences. [PDF]

Animals (Basel)
Holgado-Martín R, Risco D, Ramos A, Martínez-Pérez R, García-Jiménez WL, Hermoso-De Mendoza J, Gómez L.   +6 more
europepmc   +1 more source