Results 161 to 170 of about 424,677 (305)

"Productivity and innovation spillovers: Micro evidence from Spain" [PDF]

open access: yes
This article analyses the impact that innovation expenditure and intrasectoral and intersectoral externalities have on productivity in Spanish firms. While there is an extensive literature analysing the relationship between innovation and productivity ...
Esther Goya   +2 more
core  

Circulating levels of insulin‐like growth factor I (IGF‐I) and risk of multiple myeloma: An observational and Mendelian randomisation study

open access: yesBritish Journal of Haematology, EarlyView.
Summary Evidence for an association between insulin‐like growth factors (IGF) and multiple myeloma (MM) is inconsistent. We examined total IGF‐I concentrations and risk of MM by combining baseline serological data among UK Biobank participants (n = 444 187; 732 incident MM) with a two‐sample Mendelian randomisation (MR) analysis using identified ...
Yolanda Benavente   +56 more
wiley   +1 more source

Resistance Exercise Intervention Restores Functional Capacity and Improves Frailty Biomarkers in Centenarians. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Marcos-Perez D   +11 more
europepmc   +1 more source

"Debating as a classroom tool for adapting learning outcomes to the European higher education area" [PDF]

open access: yes
The creation of the European Higher Education Area has meant a number of significant changes to the educational structures of the university community. In particular, the new system of European credits has generated the need for innovation in the design ...
Ancor Suárez   +2 more
core  

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

"Why do municipalities cooperate to provide local public services? An empirical analysis" [PDF]

open access: yes
Intermunicipal cooperation is being increasingly adopted in various countries as a part of local service delivery reforms. This paper draws on survey data from Spain’s municipalities to examine the reasons underpinning the decisions of local governments ...
Germà Bel, Melania Mur, Xavier Fageda
core  

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

open access: yesBrain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios   +18 more
wiley   +1 more source

Patient Stratification for Serum LDH Levels Reveals Distinct CLA<sup>+</sup> T-Cell Cytokine Secretion in Response to HDM, Clinical Features and Allergic Comorbidities. [PDF]

open access: yesInt J Mol Sci
García-Jiménez I   +12 more
europepmc   +1 more source

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