Results 241 to 250 of about 424,677 (305)

Investigating the role of a conserved hydrophobic pocket of gp41 in the anti‐HIV activity of fusion inhibitors

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Membrane fusion between HIV and host cells requires interaction between the N‐terminal and C‐terminal repeat regions (NHR and CHR) of the gp41 envelope subunit. A deep hydrophobic pocket (HP) on the surface of NHR is considered crucial in this interaction.
Daniel Polo‐Megías, Mario Cano‐Muñoz, Laura Sánchez‐Martínez, Sara Lestani, Christiane Moog, Thomas Decoville, María Carmen Salinas‐García, José Antonio Gavira, Ana Cámara‐Artigas, Francisco Conejero‐Lara   +9 more
wiley   +1 more source

Rare genetic variant risks in patients with sepsis-associated acute respiratory distress syndrome. [PDF]

Respir Res
Tosco-Herrera E, Rubio-Rodríguez LA, Muñoz-Barrera A, Jáspez D, Suárez-Pajes E, Corrales A, Alonso-González A, Prieto-González M, Rodríguez-Pérez A, Carriedo D, Blanco J, Ambrós A, Lorente L, Martín MM, Solé-Violán J, Rodríguez-Gallego C, González-Higueras E, Espinosa E, Muriel-Bombin A, Domínguez D, Soro M, Hernández-Beeftink T, Añón JM, Villar J, Guillén-Guio B, Marcelino-Rodríguez I, Lorenzo-Salazar JM, González-Montelongo R, Flores C.   +28 more
europepmc   +1 more source

Gene‐specific double‐stranded RNAs induce mortality in the South African mealybug Delottococcus aberiae

Pest Management Science, Volume 82, Issue 6, Page 5184-5194, June 2026.
Gene‐specific double‐stranded RNAs effectively silence essential genes in the invasive citrus pest Delottococcus aberiae, leading to significant mortality through both microinjection and oral delivery. These results provide proof of concept for RNA interference‐based biopesticides as selective and sustainable tools for citrus integrated pest management.
Carolina Gallego‐Giraldo, Alberto Urbaneja, Omar Ruíz‐Rivero, Verónica Aragonés, Marie Guijarro‐Guijarro, José‐Antonio Daròs, Meritxell Perez‐Hedo   +6 more
wiley   +1 more source

Comparative profiling of neurological and biomarker status in type 1 diabetes and multiple sclerosis: A cross-sectional observational study. [PDF]

Brain Behav Immun Health
Cano-Cano F, Cruz-Gómez ÁJ, Forero L, Lara-Barea A, Lozano-Soto E, Espinosa-Rosso R, Rashid-López R, Alcalde-Vílchez E, Álvarez-Ramos P, Aguilar-Diosdado M, Arroba AI, González-Rosa JJ.   +11 more
europepmc   +1 more source

The role of the non‐profit sector in the efficiency of elderly social services: A bootstrap data envelopment analysis study

Annals of Public and Cooperative Economics, Volume 97, Issue 2, Page 401-424, June 2026.
Abstract Social services for the elderly are becoming increasingly important in societies where the elderly population is growing and requires specific attention to ensure their well‐being. Within these services, nursing homes play a key role, and it is therefore vital to ensure efficient management with an assessment according to their characteristics,
Georgina Solaz‐Moreno, Amadeo Fuenmayor Fernández, Teresa Savall Morera   +2 more
wiley   +1 more source

Phenotypic, proteomic, and functional analyses of cytokine-induced memory-like NK cells show two distinct subsets based on CD16 expression. [PDF]

Sci Rep
Carreira-Santos S, González-Sánchez M, López-Sejas N, Hassouneh F, González-Fernández L, Jorge I, Durán E, Pera A, Vázquez J, Solana R, Tarazona R, Casado JG.   +11 more
europepmc   +1 more source

Mitochondrial Transplantation as a New Therapeutic Approach Against Cardiac and Renal Consequences in Male Rats With Myocardial Infarction

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral, Alejandro Montoro‐Garrido, Ana Romero‐Miranda, Fabián Islas, Bunty Ramchandani, Ricardo Gredilla, Joaquín Fernández‐Irigoyen, Enrique Santamaría, Beatriz Delgado‐Valero, Sara Jiménez‐González, Raquel Rodrigues Díez, María Luisa Nieto, Victoria Cachofeiro, Ernesto Martínez‐Martínez   +13 more
wiley   +1 more source

A novel Dual-guide CRISPR-Cas13 strategy improves specificity for single-nucleotide variant detection. [PDF]

Nucleic Acids Res
Aguilar-González A, Martos-Jamai I, Ramos-Hernández I, Molina-Estévez FJ, Villao NV, Puig-Serra P, Rodríguez-Perales S, Torres R, Labun K, Sánchez-Martín RM, Díaz-Mochón JJ, Martín F.   +11 more
europepmc   +1 more source

The First Archaeomagnetic Age at Tiwanaku and Implications for Dating Andean Metallurgical Furnaces

Archaeometry, Volume 68, Issue 3, Page 317-329, June 2026.
ABSTRACT This paper presents the first archaeomagnetic dating at Tiwanaku (Andean Altiplano). We compared the geomagnetic field values recorded by a metallurgical furnace against an updated SHAWQ2k‐SH global model and a regional intensity curve, both of which include, for the first time, high‐quality intensity data from the Southern Hemisphere. Results
Judit del Río, Pablo Cruz, Miriam Gómez‐Paccard, Alicia Palencia‐Ortas, Marina Puente‐Borque, F. Javier Pavón‐Carrasco, Erik Marsh   +6 more
wiley   +1 more source

Integrating Next-Generation Sequencing Into Routine Molecular Diagnosis of Inherited Coagulation Factor Deficiencies: Real-World Data From Spanish Patients. [PDF]

Haemophilia
Borràs N, Comes N, Ramírez L, Parra R, Altisent C, Lorenzo-Vizcaya Á, Marzo-Alonso C, López-Fernández MF, Canaro M, Falcón-Rodríguez M, Cortes-Vidal Á, Rios de Paz MA, Rodríguez-García JA, Moreto-Quintana A, Bandini P, Hobeich C, Corrales I, Vidal F.   +17 more
europepmc   +1 more source